Ana Belen Caballero Hernandez

Ana Belen Caballero Hernandez

Professora agregada

Scopus Author ID: 36001770700
Researcher ID: I-1820-2014
Àrea de coneixement : Química Inorgànica

Grup de Recerca: PhotoBioCat

Informació de contacte
Departament de Química Inorgànica i Orgànica
Departament de Química Inorgànica i Orgànica - Secció Inorgànica. Facultat de Química. Universitat de Barcelona Martí i Franquès, 1-11
934039130
ana.caballero(a)ub.edu

Formació acadèmica

Licenciada en Química . Universidad de Granada . 20/07/2006 . (Diplomatura / Llicenciatura / Grau)
Doctora en Química . Universidad de Granada . 20/12/2010 . (Doctorat )
Máster Universitario en Química . Universidad de Granada . 20/11/2007 . (Màster Oficial)
Experto Universitario . Facultat de Psicologia. Universitat de Barcelona . 07/2022 . (Formació Especialitzada)

Línies d'activitat

Anti-amyloid compounds
Modulation of DNA binding to molecular drugs. DNA-nanoparticle interactions
Metal-amyloid toxicity
Photoactive metal complexes for cancer therapy

Publicacions en revistes

Caballero, A.B.; Rodríguez-Diéguez, A.; Quirós, M.; Salas, J.M.; Huertas, O.; Ramírez-Macías, I.; Olmo, F.; Marín, C.; Chaves-Lemaur, G.; Gutierrez-Sánchez, R.; Sánchez-Moreno, M. Compounds Containing First-Row Transition Metals: Towards the Next Generation of Drugs for the Neglected Infectious Chagas Disease and Leishmaniasis. En European Journal of Medicinal Chemistry. Volum 85. 2014
Brissos, R. F.; Torrents, E.; dos Santos Mello, F. M.; Pires, W. C.; de Paula Silveira-Lacerda, E.; Caballero, A. B.; Caubet, A.; Massera, C.; Roubeau, O.; Teat, S. J.; Gamez, P. Highly Cytotoxic DNA-Interacting Copper(II) Coordination Compounds. En Metallomics. Volum 6. 2014 . https://doi.org/10.1039/C4MT00152D
De la Pinta, N.; Caballero, A.B.; Madariaga, G.; Ezpeleta. T.; Rodríguez-Diéguez, A.; Salas, J.M.; Cortés, R. DPDS-DPS in situ transformation at room temperature via a 1,2-nucleophilic addition mechanism. En Crystengcomm. Volum 16. 2014 . https://doi.org/10.1039/C4CE00781F
Caballero, A.B.; Rodríguez-Diéguez, A.; Salas, J.M.; Sánchez-Moreno, M.; Marín, C.; Rodríguez-Macías, I.; Santamaría-Díaz, N.; Gutiérrez-Sánchez, R. Lanthanide complexes containing 5-methyl-1,2,4-triazolo[1,5-a] pyrimidin-7(4h)-one and their therapeutic potential to fight leishmaniasis and Chagas disease. En Journal of Inorganic Biochemistry. Volum 138. 2014 . https://doi.org/10.1016/j.jinorgbio.2014.04.016
Ana B. Caballero; Juan M. Salas; Manuel Sánchez-Moreno. Metal-Based Therapeutics for Leishmaniasis. En Leishmaniasis - Trends in Epidemiology, Diagnosis and Treatment. 2014 . https://doi.org/10.5772/57376
Gamez, P.; Caballero, A.B. Copper in Alzheimer's disease: Implications in amyloid aggregation and neurotoxicity. En AIP Advances. Volum 5. 2015 . https://doi.org/10.1063/1.4921314
Presa, A.; Brissos, R. F.; Caballero, A. B.; Borilovic, I.; Korrodi-Gregório, L.; Pérez-Tomás, R.; Roubeau, O.; Gamez, P. Photoswitching the Cytotoxic Properties of Platinum(II) Compounds. En Angewandte Chemie-International Edition. Volum 54. Número 15. 2015 . https://doi.org/10.1002/anie.201412157
Grau, J.; Brissos, R.F.; Salinas-Uber, J.; Caballero, A.B.; Caubet, A.; Roubeau, O.; Korrodi-Gregório, L.; Pérez-Tomás, R.; Gamez, P. The effect of potential supramolecular-bond promoters on the DNA-interacting abilities of copper-terpyridine compounds. En Dalton Transactions. Volum 44. 2015 . Repositori Institucional
Caballero, A.B.; Terol-Ordaz, L.; Espargaró, A.; Vázquez, G.; Nicolás, E.; Sabate, R.; Gamez, P. Histidine-rich Oligopeptides to Lessen Copper-Mediated Amyloid- Toxicity. En Chemistry-A European Journal. Volum 22. Número 21. 2016 . https://doi.org/10.1002/chem.201600286
Salas, J.M.; Caballero, A.B.; Esteban-Parra, G.M.; Méndez-Arriaga, J.M. Leishmanicidal and Trypanocidal Activity of Metal Complexes with 1,2,4-Triazolo[1,5-a]pyrimidines: Insights on their Therapeutic Potential against Leishmaniasis and Chagas Disease. En Current Medicinal Chemistry. Volum 24. Número 25. 2017 . https://doi.org/10.2174/0929867324666170516122024
V. A. Barrera-Guzmán ;E.O. Rodríguez-Hernández ;N. Ortiz-Pastrana ;R. Domínguez-González ;Ana B. Caballero; Patrick Gamez ;N. Barba-Behrens. Efficient copper-based DNA cleavers from carboxylate benzimidazole ligands. En Journal of Biological Inorganic Chemistry. Volum 23. Número 7. 2018 . https://doi.org/10.1007/s00775-018-1598-9
Mena, Silvia; Mirats, Andrea; Caballero, Ana B.; Guirado, Gonzalo; Barrios, Leoni A.; Teat, Simon J.; Rodriguez-Santiago, Luis; Sodupe, Mariona; Gamez, Patrick. Drastic Effect of the Peptide Sequence on the Copper-Binding Properties of Tripeptides and the Electrochemical Behaviour of Their Copper(II) Complexes. En Chemistry-A European Journal. Volum 24. Número 20. 2018 . https://doi.org/10.1002/chem.201704623
Grau, Jordi; Renau, Cristina; Caballero, Ana B.; Caubet, Amparo; Pockaj, Marta; Lorenzo, Julia; Gamez, Patrick. Evaluation of the metal-dependent cytotoxic behaviour of coordination compounds. En Dalton Transactions. Volum 47. Número 14. 2018 . https://doi.org/10.1039/c7dt04604a
Castro-Ramirez, Rodrigo; Ortiz-Pastrana, Naytze; Caballero, Ana B.; Zimmerman, Matthew T.; Stadelman, Bradley S.; Gaertner, Andrea A. E.; Brumaghim, Julia L.; Korrodi-Gregorio, Luis; Perez-Tomas, Ricardo; Gamez, Patrick; Barba-Behrens, Norah. DNA interactions of non-chelating tinidazole-based coordination compounds and their structural, redox and cytotoxic properties. En Dalton Transactions. Volum 47. Número 22. 2018 . https://doi.org/10.1039/c8dt00716k
Brissos, R.F.; Clavero, P.; Gallen, A.; Grabulosa, A.; Barrios, L.A.; Caballero, A.B.; Korrodi-Gregório, L.; Pérez-Tomás, R.; Muller, G.; Soto-Cerrato, V.; Gamez, P. Highly cytotoxic Ruthenium(II)-Arene complexes from bulky 1-pyrenylphosphane ligands. En Inorganic Chemistry. Volum 57. 2018 . https://doi.org/10.1021/acs.inorgchem.8b02541
Caballero, A.B.; Cardo, L.; Claire, S.; Craig, J.S.; Hodges, N.J.; Vladyka, A.; Albrecht, T.; Rochford, L.A.; Pikramenou, Z.; Hannon, M.J. Assisted delivery of anti-tumour platinum drugs using DNA-coiling gold nanoparticles bearing lumophores and intercalators: towards a new generation of multimodal nanocarriers with enhanced action. En Chemical Science. 2019
Caballero, A. B.; Espargaró, A.; Pont, C.; Busquets, M. A.; Estelrich, J.; Muñoz-Torrero, D.; Gamez, P.; Sabate, R. Bacterial inclusion bodies for anti-amyloid drug discovery: Current and future screening methods. En Current Protein & Peptide Science. 2019
Vázquez, G.; Caballero, A.B.; Kokinda, J.; Hijano, A.; Sabate, R.; Gamez, P. Copper, dityrosine cross-links and amyloid- aggregation. En Journal of Biological Inorganic Chemistry. Volum 24. Número 8. 2019 . https://doi.org/10.1007/s00775-019-01734-6
Censi, V.; Caballero, A.B.; Pérez-Hernández, M.; Soto-Cerrato, V.; Korrodi-Gregório, L.; Pérez-Tomás, R; Dell'Anna, M.M.; Mastrorill, P.; Gámez, P. DNA-binding and in vitro cytotoxic activity of platinum(II) complexes of curcumin and caffeine. En Journal of Inorganic Biochemistry. Volum 198. Número 110749. 2019 . https://doi.org/10.1016/j.jinorgbio.2019.110749
Caballero, A. B.; Iranzo, O.; Hautier, A.; Sabate, R.; Gamez, P. Peptidic Scaffolds To Reduce the Interaction of Cu(II) Ions with beta-Amyloid Protein. En Inorganic Chemistry. Volum 59. Número 1. 2020 . https://doi.org/10.1021/acs.inorgchem.9b03099
Matesanz, Ana I.; Caballero, Ana B.; Lorenzo, Carmen; Espargaro, Alba; Sabate, Raimon; Quiroga, Adoracion G.; Gamez, Patrick. Thiosemicarbazone Derivatives as Inhibitors of Amyloid-beta Aggregation: Effect of Metal Coordination. En Inorganic Chemistry. Volum 59. Número 10. 2020 . https://doi.org/10.1021/acs.inorgchem.0c00467
Caballero, Ana B.; Gamez, Patrick. Nanochaperone-Based Strategies to Control Protein Aggregation Linked to Conformational Diseases. En Angewandte Chemie-International Edition. Volum 60. Número 1. 2020 . https://doi.org/10.1002/anie.202007924
Palmeira-Mello, Marcos, V; Caballero, Ana B.; Ribeiro, Juliana Martins; de Souza-Fagundes, Elaine Maria; Gamez, Patrick; Lanznaster, Mauricio. Evaluation of cobalt(III) complexes as potential hypoxia-responsive carriers of esculetin. En Journal of Inorganic Biochemistry. Volum 211. 2020 . https://doi.org/10.1016/j.jinorgbio.2020.111211
M. V. Palmeira-Mello ;A. B. Caballero ;A. López-Espinar ;G. P. Guedes ;A. Caubet ;E. M. de Souza-Fagundes ;M. Lanznaster ;P. Gamez. DNA-interacting properties of two analogous square-planar cis-chlorido complexes: copper versus palladium. En Journal of Biological Inorganic Chemistry. Volum 26. Número 6. 2021 . Repositori Institucional
J. J. Boté Vericad, A. B. Caballero, F. Cebrià, A. Forés-Miravalles (coord..), N. Guasch-Ferré, T. Hernández (coord.), N. Moragas, D. J. Orengo, M. M. Suárez Vilagran. De la necesidad a la oportunidad: propuestas metodológicas para los nuevos tiempos. En Quaderns de Docència Universitària. Volum 44. 2021 . http://hdl.handle.net/2445/180933
Kowalczyk, J.; Grapsi, E.; Espargaró, A.; Caballero, A.B.; Juárez-Jiménez, J.; Busquets, MA.; Gamez, P.; Sabate, R.; Estelrich, J. Dual effect of Prussian Blue nanoparticles on Aβ40 aggregation: β-sheet fibril reduction and copper dyshomeostasis regulation. En Biomacromolecules. Volum 22. Número 2. 2021 . https://doi.org/10.1021/acs.biomac.0c01290
Teresa Hernández i Morlans; Anna Forés Miravalles; Juan-José Boté Vericad; Ana B. Caballero; Francesc Cebrià; Núria Guasch Ferré; Natalia Moragas; Dorcas J. Orengo; María del Mar Suárez Vilagran. De la necessitat a l'oportunitat: propostes metodològiques per als nous temps. En Quaderns de Docència Universitària. Volum 44. 2021 . http://hdl.handle.net/2445/180956
Caballero AB; Gamez P; Sabate R; Espargaró A. Anti-Amyloid Drug Screening Methods Using Bacterial Inclusion Bodies. En Methods in Molecular Biology. Volum 2538. 2022 . Repositori Institucional
Alvarez-Berbel, I.; Espargaró, A.; Viayna, A.; Caballero, A. B.; Busquets, M. A.; Gamez, P.; Luque, F. J.; Sabate, R. Three to tango: Inhibitory Effect of quercetin and apigenin on acetylcholinesterase, amyloid-β aggregation and acetylcholinesterase-amyloid interaction. En Pharmaceutics. Volum 14. Número 11. 2022 . Repositori Institucional
Guglielmo Spinelli; Ana B. Caballero; Patrick Gamez. Nanotechnological approaches to address photosensitizers' limitations: towards improved clinical applicability of photodynamic therapy. En Chemistry Squared. Volum 6. Número 2. 2022 . Repositori Institucional
Piedad Herrera-Ramírez; Sarah Alina Berger; Dana Josa; David Aguilà; Ana B. Caballero; Pere Fontova; Vanessa Soto-Cerrato; Manuel Martínez; Patrick Gamez. Steric hindrance, ligand ejection and associated photocytotoxic properties of ruthenium(II) polypyridyl complexes. En Journal of Biological Inorganic Chemistry. Volum 28. 2023 . Repositori Institucional
Palmeira-Mello, M. V.; Caballero, A. B.; Herrera-Ramirez, P.; Costa, A. R.; Santana, S. S.; Guedes, G. P.; Caubet, A.; Batista, A. A.; Gamez, P.; Lanznaster, M. Cobalt(III)-py(2)en systems as potential carriers of beta-ketoester-based ligands. En Journal of Inorganic Biochemistry. Volum 248. 2023 . https://doi.org/10.1016/j.jinorgbio.2023.112345
J. Anacleto-Santos ;N. Rivera-Fernández ;F. Sánchez-Bartez ;I. Gracia-Mora ;A.B. Caballero ;P. Gamez ;N. Barba-Behrens. Anti-toxoplasma activity and DNA-binding of copper(II) and zinc(II) coordination compounds with 5-nitroimidazole-based ligands. En Journal of Biological Inorganic Chemistry. 2023 . https://doi.org/10.1007/s00775-023-02029-7

Estades a Centres de Recerca

School of Chemistry. University of Birmingham. Birmingham. REGNE UNIT. 2011
University of Oslo. Oslo. NORUEGA. 2014