Ana Belen Caballero Hernandez
Senior lecturer
Knowledge area: Química Inorgànica
Research group:
PhotoBioCat
Academic training
Licenciada en Química
. Universidad de Granada
. 20/07/2006
. (Diploma / Degree / Activities)
Doctora en Química
. Universidad de Granada
. 20/12/2010
. (Ph.D.)
Máster Universitario en Química
. Universidad de Granada
. 20/11/2007
. (Official Master)
Experto Universitario
. Facultat de Psicologia. Universitat de Barcelona
. 07/2022
. (Specialized Training)
Research interests
Anti-amyloid compounds
Modulation of DNA binding to molecular drugs. DNA-nanoparticle interactions
Metal-amyloid toxicity
Photoactive metal complexes for cancer therapy
Journal Publications
Caballero, A.B.; Rodríguez-Diéguez, A.; Quirós, M.; Salas, J.M.; Huertas, O.; Ramírez-Macías, I.; Olmo, F.; Marín, C.; Chaves-Lemaur, G.; Gutierrez-Sánchez, R.; Sánchez-Moreno, M.
Compounds Containing First-Row Transition Metals: Towards the Next Generation of Drugs for the Neglected Infectious Chagas Disease and Leishmaniasis.
In
European Journal of Medicinal Chemistry.
Volume 85.
2014
Brissos, R. F.; Torrents, E.; dos Santos Mello, F. M.; Pires, W. C.; de Paula Silveira-Lacerda, E.; Caballero, A. B.; Caubet, A.; Massera, C.; Roubeau, O.; Teat, S. J.; Gamez, P.
Highly Cytotoxic DNA-Interacting Copper(II) Coordination Compounds.
In
Metallomics.
Volume 6.
2014
. https://doi.org/10.1039/C4MT00152D
De la Pinta, N.; Caballero, A.B.; Madariaga, G.; Ezpeleta. T.; Rodríguez-Diéguez, A.; Salas, J.M.; Cortés, R.
DPDS-DPS in situ transformation at room temperature via a 1,2-nucleophilic addition mechanism.
In
Crystengcomm.
Volume 16.
2014
. https://doi.org/10.1039/C4CE00781F
Caballero, A.B.; Rodríguez-Diéguez, A.; Salas, J.M.; Sánchez-Moreno, M.; Marín, C.; Rodríguez-Macías, I.; Santamaría-Díaz, N.; Gutiérrez-Sánchez, R.
Lanthanide complexes containing 5-methyl-1,2,4-triazolo[1,5-a] pyrimidin-7(4h)-one and their therapeutic potential to fight leishmaniasis and Chagas disease.
In
Journal of Inorganic Biochemistry.
Volume 138.
2014
. https://doi.org/10.1016/j.jinorgbio.2014.04.016
Ana B. Caballero; Juan M. Salas; Manuel Sánchez-Moreno.
Metal-Based Therapeutics for Leishmaniasis.
In
Leishmaniasis - Trends in Epidemiology, Diagnosis and Treatment.
2014
. https://doi.org/10.5772/57376
Gamez, P.; Caballero, A.B.
Copper in Alzheimer's disease: Implications in amyloid aggregation and neurotoxicity.
In
AIP Advances.
Volume 5.
2015
. https://doi.org/10.1063/1.4921314
Presa, A.; Brissos, R. F.; Caballero, A. B.; Borilovic, I.; Korrodi-Gregório, L.; Pérez-Tomás, R.; Roubeau, O.; Gamez, P.
Photoswitching the Cytotoxic Properties of Platinum(II) Compounds.
In
Angewandte Chemie-International Edition.
Volume 54.
Number 15.
2015
. https://doi.org/10.1002/anie.201412157
Grau, J.; Brissos, R.F.; Salinas-Uber, J.; Caballero, A.B.; Caubet, A.; Roubeau, O.; Korrodi-Gregório, L.; Pérez-Tomás, R.; Gamez, P.
The effect of potential supramolecular-bond promoters on the DNA-interacting abilities of copper-terpyridine compounds.
In
Dalton Transactions.
Volume 44.
2015
. Institutional Repository
Caballero, A.B.; Terol-Ordaz, L.; Espargaró, A.; Vázquez, G.; Nicolás, E.; Sabate, R.; Gamez, P.
Histidine-rich Oligopeptides to Lessen Copper-Mediated Amyloid- Toxicity.
In
Chemistry-A European Journal.
Volume 22.
Number 21.
2016
. https://doi.org/10.1002/chem.201600286
Salas, J.M.; Caballero, A.B.; Esteban-Parra, G.M.; Méndez-Arriaga, J.M.
Leishmanicidal and Trypanocidal Activity of Metal Complexes with 1,2,4-Triazolo[1,5-a]pyrimidines: Insights on their Therapeutic Potential against Leishmaniasis and Chagas Disease.
In
Current Medicinal Chemistry.
Volume 24.
Number 25.
2017
. https://doi.org/10.2174/0929867324666170516122024
V. A. Barrera-Guzmán ;E.O. Rodríguez-Hernández ;N. Ortiz-Pastrana ;R. Domínguez-González ;Ana B. Caballero; Patrick Gamez ;N. Barba-Behrens.
Efficient copper-based DNA cleavers from carboxylate benzimidazole ligands.
In
Journal of Biological Inorganic Chemistry.
Volume 23.
Number 7.
2018
. https://doi.org/10.1007/s00775-018-1598-9
Mena, Silvia; Mirats, Andrea; Caballero, Ana B.; Guirado, Gonzalo; Barrios, Leoni A.; Teat, Simon J.; Rodriguez-Santiago, Luis; Sodupe, Mariona; Gamez, Patrick.
Drastic Effect of the Peptide Sequence on the Copper-Binding Properties of Tripeptides and the Electrochemical Behaviour of Their Copper(II) Complexes.
In
Chemistry-A European Journal.
Volume 24.
Number 20.
2018
. https://doi.org/10.1002/chem.201704623
Grau, Jordi; Renau, Cristina; Caballero, Ana B.; Caubet, Amparo; Pockaj, Marta; Lorenzo, Julia; Gamez, Patrick.
Evaluation of the metal-dependent cytotoxic behaviour of coordination compounds.
In
Dalton Transactions.
Volume 47.
Number 14.
2018
. https://doi.org/10.1039/c7dt04604a
Castro-Ramirez, Rodrigo; Ortiz-Pastrana, Naytze; Caballero, Ana B.; Zimmerman, Matthew T.; Stadelman, Bradley S.; Gaertner, Andrea A. E.; Brumaghim, Julia L.; Korrodi-Gregorio, Luis; Perez-Tomas, Ricardo; Gamez, Patrick; Barba-Behrens, Norah.
DNA interactions of non-chelating tinidazole-based coordination compounds and their structural, redox and cytotoxic properties.
In
Dalton Transactions.
Volume 47.
Number 22.
2018
. https://doi.org/10.1039/c8dt00716k
Brissos, R.F.; Clavero, P.; Gallen, A.; Grabulosa, A.; Barrios, L.A.; Caballero, A.B.; Korrodi-Gregório, L.; Pérez-Tomás, R.; Muller, G.; Soto-Cerrato, V.; Gamez, P.
Highly cytotoxic Ruthenium(II)-Arene complexes from bulky 1-pyrenylphosphane ligands.
In
Inorganic Chemistry.
Volume 57.
2018
. https://doi.org/10.1021/acs.inorgchem.8b02541
Caballero, A.B.; Cardo, L.; Claire, S.; Craig, J.S.; Hodges, N.J.; Vladyka, A.; Albrecht, T.; Rochford, L.A.; Pikramenou, Z.; Hannon, M.J.
Assisted delivery of anti-tumour platinum drugs using DNA-coiling gold nanoparticles bearing lumophores and intercalators: towards a new generation of multimodal nanocarriers with enhanced action.
In
Chemical Science.
2019
Caballero, A. B.; Espargaró, A.; Pont, C.; Busquets, M. A.; Estelrich, J.; Muñoz-Torrero, D.; Gamez, P.; Sabate, R.
Bacterial inclusion bodies for anti-amyloid drug discovery: Current and future screening methods.
In
Current Protein & Peptide Science.
2019
Vázquez, G.; Caballero, A.B.; Kokinda, J.; Hijano, A.; Sabate, R.; Gamez, P.
Copper, dityrosine cross-links and amyloid- aggregation.
In
Journal of Biological Inorganic Chemistry.
Volume 24.
Number 8.
2019
. https://doi.org/10.1007/s00775-019-01734-6
Censi, V.; Caballero, A.B.; Pérez-Hernández, M.; Soto-Cerrato, V.; Korrodi-Gregório, L.; Pérez-Tomás, R; Dell'Anna, M.M.; Mastrorill, P.; Gámez, P.
DNA-binding and in vitro cytotoxic activity of platinum(II) complexes of curcumin and caffeine.
In
Journal of Inorganic Biochemistry.
Volume 198.
Number 110749.
2019
. https://doi.org/10.1016/j.jinorgbio.2019.110749
Caballero, A. B.; Iranzo, O.; Hautier, A.; Sabate, R.; Gamez, P.
Peptidic Scaffolds To Reduce the Interaction of Cu(II) Ions with beta-Amyloid Protein.
In
Inorganic Chemistry.
Volume 59.
Number 1.
2020
. https://doi.org/10.1021/acs.inorgchem.9b03099
Matesanz, Ana I.; Caballero, Ana B.; Lorenzo, Carmen; Espargaro, Alba; Sabate, Raimon; Quiroga, Adoracion G.; Gamez, Patrick.
Thiosemicarbazone Derivatives as Inhibitors of Amyloid-beta Aggregation: Effect of Metal Coordination.
In
Inorganic Chemistry.
Volume 59.
Number 10.
2020
. https://doi.org/10.1021/acs.inorgchem.0c00467
Caballero, Ana B.; Gamez, Patrick.
Nanochaperone-Based Strategies to Control Protein Aggregation Linked to Conformational Diseases.
In
Angewandte Chemie-International Edition.
Volume 60.
Number 1.
2020
. https://doi.org/10.1002/anie.202007924
Palmeira-Mello, Marcos, V; Caballero, Ana B.; Ribeiro, Juliana Martins; de Souza-Fagundes, Elaine Maria; Gamez, Patrick; Lanznaster, Mauricio.
Evaluation of cobalt(III) complexes as potential hypoxia-responsive carriers of esculetin.
In
Journal of Inorganic Biochemistry.
Volume 211.
2020
. https://doi.org/10.1016/j.jinorgbio.2020.111211
M. V. Palmeira-Mello ;A. B. Caballero ;A. López-Espinar ;G. P. Guedes ;A. Caubet ;E. M. de Souza-Fagundes ;M. Lanznaster ;P. Gamez.
DNA-interacting properties of two analogous square-planar cis-chlorido complexes: copper versus palladium.
In
Journal of Biological Inorganic Chemistry.
Volume 26.
Number 6.
2021
. Institutional Repository
J. J. Boté Vericad, A. B. Caballero, F. Cebrià, A. Forés-Miravalles (coord..), N. Guasch-Ferré, T. Hernández (coord.), N. Moragas, D. J. Orengo, M. M. Suárez Vilagran.
De la necesidad a la oportunidad: propuestas metodológicas para los nuevos tiempos.
In
Quaderns de Docència Universitària.
Volume 44.
2021
. http://hdl.handle.net/2445/180933
Kowalczyk, J.; Grapsi, E.; Espargaró, A.; Caballero, A.B.; Juárez-Jiménez, J.; Busquets, MA.; Gamez, P.; Sabate, R.; Estelrich, J.
Dual effect of Prussian Blue nanoparticles on Aβ40 aggregation: β-sheet fibril reduction and copper dyshomeostasis regulation.
In
Biomacromolecules.
Volume 22.
Number 2.
2021
. https://doi.org/10.1021/acs.biomac.0c01290
Teresa Hernández i Morlans; Anna Forés Miravalles; Juan-José Boté Vericad; Ana B. Caballero; Francesc Cebrià; Núria Guasch Ferré; Natalia Moragas; Dorcas J. Orengo; María del Mar Suárez Vilagran.
De la necessitat a l'oportunitat: propostes metodològiques per als nous temps.
In
Quaderns de Docència Universitària.
Volume 44.
2021
. http://hdl.handle.net/2445/180956
Caballero AB; Gamez P; Sabate R; Espargaró A.
Anti-Amyloid Drug Screening Methods Using Bacterial Inclusion Bodies.
In
Methods in Molecular Biology.
Volume 2538.
2022
. Institutional Repository
Alvarez-Berbel, I.; Espargaró, A.; Viayna, A.; Caballero, A. B.; Busquets, M. A.; Gamez, P.; Luque, F. J.; Sabate, R.
Three to tango: Inhibitory Effect of quercetin and apigenin on acetylcholinesterase, amyloid-β aggregation and acetylcholinesterase-amyloid interaction.
In
Pharmaceutics.
Volume 14.
Number 11.
2022
. Institutional Repository
Guglielmo Spinelli; Ana B. Caballero; Patrick Gamez.
Nanotechnological approaches to address photosensitizers' limitations: towards improved clinical applicability of photodynamic therapy.
In
Chemistry Squared.
Volume 6.
Number 2.
2022
. Institutional Repository
Piedad Herrera-Ramírez; Sarah Alina Berger; Dana Josa; David Aguilà; Ana B. Caballero; Pere Fontova; Vanessa Soto-Cerrato; Manuel Martínez; Patrick Gamez.
Steric hindrance, ligand ejection and associated photocytotoxic properties of ruthenium(II) polypyridyl complexes.
In
Journal of Biological Inorganic Chemistry.
Volume 28.
2023
. Institutional Repository
Palmeira-Mello, M. V.; Caballero, A. B.; Herrera-Ramirez, P.; Costa, A. R.; Santana, S. S.; Guedes, G. P.; Caubet, A.; Batista, A. A.; Gamez, P.; Lanznaster, M.
Cobalt(III)-py(2)en systems as potential carriers of beta-ketoester-based ligands.
In
Journal of Inorganic Biochemistry.
Volume 248.
2023
. https://doi.org/10.1016/j.jinorgbio.2023.112345
Guillem Vázquez; Ana B. Caballero.
Linking copper, tyrosines and protein aggregation in Alzheimer's disease.
In
Atlas of Science.
2023
. https://atlasofscience.org/linking-copper-tyrosines-and-protein-aggregation-in-alzheimers-disease/
J. Anacleto-Santos ;N. Rivera-Fernández ;F. Sánchez-Bartez ;I. Gracia-Mora ;A.B. Caballero ;P. Gamez ;N. Barba-Behrens.
Anti-toxoplasma activity and DNA-binding of copper(II) and zinc(II) coordination compounds with 5-nitroimidazole-based ligands.
In
Journal of Biological Inorganic Chemistry.
2023
. https://doi.org/10.1007/s00775-023-02029-7
Stays abroad
School of Chemistry. University of Birmingham.
Birmingham.
UNITED KINGDOM.
2011
University of Oslo.
Oslo.
NORWAY.
2014
