Informació de contacte
Departament de Farmacologia, Toxicologia i Química Terapèutica
sandra.codony(a)ub.edu
Formació acadèmica
Grau de Farmàcia
From the design to the in vivo evaluation of novel soluble epoxide hydrolase inhibitors
Postgraduate Course in Technology Transfer: from Scientific Knowledge to the Market
Projectes
Medicinal Chemistry and Pharmacology of Neurodegenerative diseases
.
2022 - 2026
. Ref.2021 SGR 00357
. Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR)
. IP: Maria Carmen Escolano MironInnovació docent: implementació de sistemes de qualitat als laboratoris docents
.
2024 - 2025
. Ref.GINDO-UB/213
. Universitat de Barcelona
. IP: Sandra Codony Gisbert
Publicacions rellevants
Leiva, R.; Barniol-Xicota, M.; Codony, S.; Ginex, T.; Vanderlinden, E.; Montes, M.; Caffrey, M.; Luque, F. J.; Naesens, L.; Vázquez, S. Aniline-Based Inhibitors of Influenza H1N1 Virus Acting on Hemagglutinin-Mediated Fusion.
En
Journal of Medicinal Chemistry.
Volum 61.
Número 1.
2018
. https://doi.org/10.1021/acs.jmedchem.7b00908Pallas, Merce; Grinan-Ferre, Christian; Dolors Puigoriol-Illamola, M.; Companys-Alemany, Julia; Corpas, Ruben; Sanfeliu, Coral; Codony, Sandra; Leiva, Rosana; Galdeano, Carles. Targeting soluble epoxide hydrolase to improve neurodegenerative traits in SAMP8 mouse.
En
Basic & Clinical Pharmacology & Toxicology.
Volum 125.
2019Codony, S.; Pont, C.; Griñán-Ferré, C.; Di Pede-Mattatelli, A.; Calvó-Tusell, C.; Feixas, F.; Osuna, S.; Jarné-Ferrer, J.; Naldi, M.; Bartolini, M.; Loza, M. I.; Brea, J.; Pérez, B.; Bartra, C.; Sanfeliu, C.; Juárez-Jiménez, J.; Morisseau, C.; Hammock, B. D.; Pallàs, M.; Vázquez, S.; Muñoz-Torrero, D. Discovery and in vivo proof of concept of a highly potent dual inhibitor of soluble epoxide hydrolase and acetylcholinesterase for the treatment of Alzheimer's disease.
En
Journal of Medicinal Chemistry.
Volum 65.
Número 6.
2022
. Repositori InstitucionalCodony, S.; Entrena, J. M.; Calvó-Tusell, C.; Jora, B.; González-Cano, R.; Osuna, S.; Corpas, R.; Morisseau, C.; Pérez, B.; Barniol-Xicota, M.; Griñán-Ferré, C.; Pérez, C.; Rodríguez-Franco, M. I.; Martínez, A. L.; Loza, M. I.; Pallàs, M.; Verhelst, S. H. L.; Sanfeliu, C.; Feixas, F.; Hammock, B. D.; Brea, J.; Cobos, E. J.; Vázquez, S. Synthesis, in vitro profiling, and in vivo evaluation of benzohomoadamantane-based ureas for visceral pain: a new indication for soluble epoxide hydrolase inhibitors.
En
Journal of Medicinal Chemistry.
Volum 65.
Número 20.
2022
. Repositori InstitucionalCodony S; Calvó-Tusell C; Valverde E; Osuna S; Morisseau C; Loza MI; Brea J; Pérez C; Rodríguez-Franco MI; Pizarro-Delgado J; Corpas R; Griñán-Ferré C; Pallàs M; Sanfeliu C; Vázquez-Carrera M; Hammock BD; Feixas F; Vázquez S. From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis.
En
Journal of Medicinal Chemistry.
Volum 64.
Número 9.
2021
. https://doi.org/10.1021/acs.jmedchem.0c01601Griñán-Ferré, C.; Companys-Alemany, J.; Jarné-Ferrer, J.; Codony, S.; González-Castillo, C.; Ortuño-Sahagún, D.; Vilageliu, L.; Grinberg, D.; Vazquez, S.; Pallàs, M. Soluble epoxide hydrolase inhibition ameliorates phenotype 2 and cognitive capabilities in a murine model of Niemann Pick disease type C.
En
International Journal of Molecular Sciences.
Volum 22.
Número 7.
2021
. Repositori InstitucionalCodony S; Pujol E; Pizarro J; Feixas F; Valverde E; Loza MI; Brea JM; Saez E; Oyarzabal J; Pineda-Lucena A; Pérez B; Pérez C; Rodríguez-Franco MI; Leiva R; Osuna S; Morisseau C; Hammock BD; Vázquez-Carrera M; Vázquez S. 2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis.
En
Journal of Medicinal Chemistry.
Volum 63.
Número 17.
2020
. https://doi.org/10.1021/acs.jmedchem.0c00310Codony, S.; Valverde, E.; Leiva, R.; Brea, J.; Loza, M. I.; Morisseau, C.; Hammock, B. D.; Vázquez, S. Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors.
En
Bioorganic & Medicinal Chemistry.
Volum 27.
Número 20.
2019
. https://doi.org/10.1016/j.bmc.2019.115078Griñán-Ferré, C.; Jarné-Ferrer, J.; Bellver-Sanchís, A.; Codony, S.; Puigoriol-Illamola, D.; Sanfeliu, C.; Oh, Y.; Lee, S.; Vázquez, S.; Pallàs, M. Novel molecular mechanism driving neuroprotection after soluble epoxide hydrolase inhibition: Insights for Alzheimer's disease therapeutics.
En
CNS Neuroscience & Therapeutics.
2023
. https://doi.org/10.1111/cns.14511Jarne-Ferrer, J.; Sánchez, J.; Codony, S.; Schneider, M.; Müller, C.E.; Sanfeliu, C.; Franco, R.; Vazquez, S.; Griñán-Ferré, C.; Pallàs, M. Novel Soluble Epoxide Hydrolase Inhibitor: Toward Regulatory Preclinical Studies.
En
ACS Pharmacology and Translational Science.
2025
. Repositori Institucional
Patents, Programari i Bases de dades
Polycyclic compounds as soluble epoxide hydrolase inhibitors (Organització Euroasiàtica de Patents, 18/01/2021)
Compounds as soluble epoxide hydrolase inhibitors (Països Membres de la Convenció Europea de Patents, 24/03/2021)