Sandra Codony Gisbert

Lecturer Professor

ORCID: 0000-0003-0539-673X
Knowledge area: Química Orgànica

Contact Information
Department of Pharmacology, Toxicology and Medicinal Chemistry


sandra.codony(a)ub.edu

Academic training

Grau de Farmàcia
From the design to the in vivo evaluation of novel soluble epoxide hydrolase inhibitors
Postgraduate Course in Technology Transfer: from Scientific Knowledge to the Market

Projects

Medicinal Chemistry and Pharmacology of Neurodegenerative diseases . 2022 - 2026 . Ref.2021 SGR 00357 . Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR) . PI: Maria Carmen Escolano Miron
Innovació docent: implementació de sistemes de qualitat als laboratoris docents . 2024 - 2025 . Ref.GINDO-UB/213 . Universitat de Barcelona . PI: Sandra Codony Gisbert

Relevant publications

Leiva, R.; Barniol-Xicota, M.; Codony, S.; Ginex, T.; Vanderlinden, E.; Montes, M.; Caffrey, M.; Luque, F. J.; Naesens, L.; Vázquez, S. Aniline-Based Inhibitors of Influenza H1N1 Virus Acting on Hemagglutinin-Mediated Fusion. In Journal of Medicinal Chemistry. Volume 61. Number 1. 2018 . https://doi.org/10.1021/acs.jmedchem.7b00908
Pallas, Merce; Grinan-Ferre, Christian; Dolors Puigoriol-Illamola, M.; Companys-Alemany, Julia; Corpas, Ruben; Sanfeliu, Coral; Codony, Sandra; Leiva, Rosana; Galdeano, Carles. Targeting soluble epoxide hydrolase to improve neurodegenerative traits in SAMP8 mouse. In Basic & Clinical Pharmacology & Toxicology. Volume 125. 2019
Codony, S.; Pont, C.; Griñán-Ferré, C.; Di Pede-Mattatelli, A.; Calvó-Tusell, C.; Feixas, F.; Osuna, S.; Jarné-Ferrer, J.; Naldi, M.; Bartolini, M.; Loza, M. I.; Brea, J.; Pérez, B.; Bartra, C.; Sanfeliu, C.; Juárez-Jiménez, J.; Morisseau, C.; Hammock, B. D.; Pallàs, M.; Vázquez, S.; Muñoz-Torrero, D. Discovery and in vivo proof of concept of a highly potent dual inhibitor of soluble epoxide hydrolase and acetylcholinesterase for the treatment of Alzheimer's disease. In Journal of Medicinal Chemistry. Volume 65. Number 6. 2022 . Institutional Repository
Codony, S.; Entrena, J. M.; Calvó-Tusell, C.; Jora, B.; González-Cano, R.; Osuna, S.; Corpas, R.; Morisseau, C.; Pérez, B.; Barniol-Xicota, M.; Griñán-Ferré, C.; Pérez, C.; Rodríguez-Franco, M. I.; Martínez, A. L.; Loza, M. I.; Pallàs, M.; Verhelst, S. H. L.; Sanfeliu, C.; Feixas, F.; Hammock, B. D.; Brea, J.; Cobos, E. J.; Vázquez, S. Synthesis, in vitro profiling, and in vivo evaluation of benzohomoadamantane-based ureas for visceral pain: a new indication for soluble epoxide hydrolase inhibitors. In Journal of Medicinal Chemistry. Volume 65. Number 20. 2022 . Institutional Repository
Codony S; Calvó-Tusell C; Valverde E; Osuna S; Morisseau C; Loza MI; Brea J; Pérez C; Rodríguez-Franco MI; Pizarro-Delgado J; Corpas R; Griñán-Ferré C; Pallàs M; Sanfeliu C; Vázquez-Carrera M; Hammock BD; Feixas F; Vázquez S. From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis. In Journal of Medicinal Chemistry. Volume 64. Number 9. 2021 . https://doi.org/10.1021/acs.jmedchem.0c01601
Griñán-Ferré, C.; Companys-Alemany, J.; Jarné-Ferrer, J.; Codony, S.; González-Castillo, C.; Ortuño-Sahagún, D.; Vilageliu, L.; Grinberg, D.; Vazquez, S.; Pallàs, M. Soluble epoxide hydrolase inhibition ameliorates phenotype 2 and cognitive capabilities in a murine model of Niemann Pick disease type C. In International Journal of Molecular Sciences. Volume 22. Number 7. 2021 . Institutional Repository
Codony S; Pujol E; Pizarro J; Feixas F; Valverde E; Loza MI; Brea JM; Saez E; Oyarzabal J; Pineda-Lucena A; Pérez B; Pérez C; Rodríguez-Franco MI; Leiva R; Osuna S; Morisseau C; Hammock BD; Vázquez-Carrera M; Vázquez S. 2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis. In Journal of Medicinal Chemistry. Volume 63. Number 17. 2020 . https://doi.org/10.1021/acs.jmedchem.0c00310
Codony, S.; Valverde, E.; Leiva, R.; Brea, J.; Loza, M. I.; Morisseau, C.; Hammock, B. D.; Vázquez, S. Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors. In Bioorganic & Medicinal Chemistry. Volume 27. Number 20. 2019 . https://doi.org/10.1016/j.bmc.2019.115078
Griñán-Ferré, C.; Jarné-Ferrer, J.; Bellver-Sanchís, A.; Codony, S.; Puigoriol-Illamola, D.; Sanfeliu, C.; Oh, Y.; Lee, S.; Vázquez, S.; Pallàs, M. Novel molecular mechanism driving neuroprotection after soluble epoxide hydrolase inhibition: Insights for Alzheimer's disease therapeutics. In CNS Neuroscience & Therapeutics. 2023 . https://doi.org/10.1111/cns.14511
Jarne-Ferrer, J.; Sánchez, J.; Codony, S.; Schneider, M.; Müller, C.E.; Sanfeliu, C.; Franco, R.; Vazquez, S.; Griñán-Ferré, C.; Pallàs, M. Novel Soluble Epoxide Hydrolase Inhibitor: Toward Regulatory Preclinical Studies. In ACS Pharmacology and Translational Science. 2025 . Institutional Repository

Patents, Software and Database

Polycyclic compounds as soluble epoxide hydrolase inhibitors (Euroasian Patent Office, 18/01/2021)
Compounds as soluble epoxide hydrolase inhibitors (European Patent Convention Countries, 24/03/2021)