Marina Corbella Morato. Facultat de Farmàcia i Ciències de l'Alimentació (UB)

Projectes

Dissecting and Engineering Allosteric Activation in a Biosynthetic Enzyme . 2020 . Ref.890562 . European Commission . IP: Marina Corbella Morató, Shina Carolin Lynn Kamerlin

Extended ABO antigens: the missing link for the enzymatic production of universal donor blood . 2023 - 2027 . Ref.0077684 . Novo Nordisk Foundation . IP: Maher Abou Hachem

Engineering substrate specificities towards the enzymatic production of universal type O blood . 2025 - 2025 . Ref.BCV-2025-2-0022 . Red Española de Supercomputación . IP: Marina Corbella Morato

Understanding the birth of new enzymes on old scaffolds . 2019 - 2024 . Ref.KAW2018.0140 . The Knut and Alice Wallenberg Foundation . IP: Shina Caroline Lynn Kamerlin

Biologia Computacional i Disseny de Fàrmacs . 2017 - 2021 . Ref.2017SGR1746 . Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR) . IP: Francisco Javier Luque Garriga

Simulación atomística de la dinámica de transferencia de energía en complejos pigmento-proteína fotosintéticos . 2013 - 2015 . Ref.CTQ2012-36195 . Ministerio de Economía y Competitividad . IP: Carles Eduard Curutchet Barat

Structure-based modeling of the role of the environment in photosynthetic light harvesting and protein fluorescence

. 2018 . Ref.CTQ2017-89924-P . Ministerio de Ciencia Innovación y Universidades del Gobierno de España . IP: Carles Eduard Curutchet Barat

Physical Constraints for Accessing Genomic Information . 2017 - 2022 . Ref.KAW2016.0077 . The Knut and Alice Wallenberg Foundation . IP: Johan Elf

Activity-Based Profiling of Glycoprocessing Enzymes for Human Health and a Sustainable Society . 2021 . Ref.951231 . European Research Council . IP: Carme Rovira Virgili

Publicacions rellevants

Fisher, G.; Corbella, M.; Alphey, M. S.; Nicholson, J.; Read, B. J.; Kamerlin, S. C. L.; da Silva, R. G. Allosteric rescue of catalytically impaired ATP phosphoribosyltransferase variants links protein dynamics to active-site electrostatic preorganisation. En Nature Communications. Volum 13. 2022 . https://doi.org/10.1038/s41467-022-34960-9

Pinto, G. P.; Corbella, M.; Demkiv, A. O.; Kamerlin, S. C. L. Exploiting enzyme evolution for computational protein design. En Trends in Biochemical Sciences. Volum 47. Número 5. 2021 . https://doi.org/10.1016/j.tibs.2021.08.008

Corbella, M.; Pinto, G. P.; Kamerlin, S. C. L. Loop dynamics and the evolution of enzyme activity. En Nature Reviews Chemistry. Volum 7. Número 536. 2023 . https://doi.org/10.1038/s41570-023-00495-w

Corbella, M.; Liao, Q.; Moreira, C.; Parracino, A.; Kasson, P. M.; Kamerlin, S. C. L. The N-terminal helix-turn-helix motif of transcription factors MarA and Rob drives DNA recognition. En Journal of Physical Chemistry B. Volum 125. Número 25. 2021 . https://doi.org/10.1021/acs.jpcb.1c00771

Corbella, M.; Moreira, C.; Bello-Madruga, R.; Torrent, M.; Kamerlin, S. C. L.; Blair, J. M. A.; Sancho-Vaello, E. Targeting MarA N-terminal domain dynamics to prevent DNA binding. En Protein Science. Volum 34. Número 1. 2024 . https://doi.org/10.1002/pro.5258

Romero-Rivera, A.; Corbella, M.; Parracino, A.; Patrick, W. M.; Kamerlin, S. C. L. Complex loop dynamics underpin activity, specificity, and evolvability in the (βα)8 barrel enzymes of histidine and tryptophan biosynthesis. En JACS Au. Volum 2. Número 4. 2022 . https://doi.org/10.1021/jacsau.2c00063

Corbella, M.; Bravo, J.; Demkiv, A. O.; Calixto, A. R.; Sompiyachoke, K.; Bergonzi, C.; Brownless, A. L. R.; Elias, M. H.; Kamerlin, S. C. L. Catalytic redundancies and conformational plasticity drives selectivity and promiscuity in quorum quenching lactonases. En JACS Au. Volum 4. Número 9. 2024 . https://doi.org/10.1021/jacsau.4c00404

Corbella, M.; Voityuk, A.A.; Curutchet, C. Single amino acid mutation controls hole transfer dynamics in DNA-methyltransferase HhaI complexes. En Journal of Physical Chemistry Letters. Volum 6. Número 18. 2015 . Repositori Institucional

Corbella, M.; Voityuk, A.A.; Curutchet, C. How abasic sites impact hole transfer dynamics in GC-rich DNA sequences. En Physical Chemistry Chemical Physics. Volum 20. Número 35. 2018 . Repositori Institucional

Marina Corbella Morato

Projectes

Publicacions rellevants

Patents, Programari i Bases de dades