Ester Lozano Garcia

Lecturer Professor

Researcher ID: H-2215-2014

Knowledge area: Immunologia

Contact Information
Department of Cell Biology, Physiology and Immunology
Avinguda Diagonal, 643

elozano(a)ub.edu

Stays abroad in Research Centers

Boston. UNITED STATES. 2009 (1 Years 3 Months) . Center for Neurologic Diseases (Harvard Medical School - Brigham and Women´s Hospital) . Postdoctoral

New Haven. UNITED STATES. 2010 (3 Years 5 Months) . Dept. Neurology and Immunobiology (Yale School of Medicine) . Postdoctoral

Academic training

Biologia . Universitat de Barcelona . 1994 . (Diploma / Degree / Activities)

Doctor de la Universitat de Barcelona . Universitat de Barcelona . 26/05/2008 . (Ph.D.)

Biotecnologia . Universitat de Barcelona . 1997 . (Official Master)

Activity interests

Mechanisms of immune regulation in humans . (01/03/2009)

immunotherapy
Immune Checkpoint

Projects

Identificación de los mecanismos inmunológicos que controlan la progresión a mieloma en los pacientes con mieloma quiescente 'non-evolving' y 'evolving' para el diseño de nuevas estrategias terapéuticas (Programa Nacional de Salud) . 2021 - 2023 . Ref.PI20/00436 . Ministerio de Ciencia, Innovación y Universidades . PI: Laura Rosiñol Dachs; Ester Lozano Garcia . (5 Researchers)

Mecanismos de control inmunológico involucrados en la progresión tras tratamiento en el mieloma múltiple () . 2017 - 2019 . Ref.PI16/00423 (PI044505) . Instituto de Salud Carlos III . PI: Carlos Fernández de Larrea

Journal Publications

Lozano, Ester; Mena, Mari-Pau; Díaz, Tania; Martin-Antonio, Beatriz; Leon, Sheila; Rodríguez-Lobato, Luis Gerardo; Oliver-Caldés, Aina; Cibeira, Maria Teresa; Bladé, Joan; Prat, Aleix; Rosinol, Laura; Fernández de Larrea, Carlos (2020). Nectin-2 Expression on Malignant Plasma Cells Is Associated With Better Response to TIGIT Blockade in Multiple Myeloma. Clinical Cancer Research, 26(17), pp. 4688 - 4698 . Institutional Repository . ISSN: 1078-0432

Martín-Antonio, B.; Suñe, G.; Najjar, A.; Perez-Amill, L.; Antoñana-Vildosola, A.; Castella, M.; León, S.; Velasco-de Andrés, M.; Lozano, F.; Lozano, E.; Bueno, C.; Estanyol, J.M.; Muñoz-Pinedo, C.; Robinson, S.N.; Urbano-Ispizua, A. (2019). Extracellular NK histones promote immune cell anti-tumor activity by inducing cell clusters through binding to CD138 receptor. Journal for ImmunoTherapy of Cancer , 7, p. 259 . Institutional Repository . ISSN: 2051-1426

Lozano, Ester; Diaz, Tania; Mena, Mari-Pau; Sune, Guillermo; Calvo, Xavier; Calderon, Marcos; Perez-Amill, Lorena; Rodriguez, Vanina; Perez-Galan, Patricia; Roue, Gael; Teresa Cibeira, M.; Rosinol, Laura; Isola, Ignacio; Rodriguez-Lobato, Luis-Gerardo; Martin-Antonio, Beatriz; Blade, Joan; Fernandez De larrea, Carlos (2018). Loss of the Immune Checkpoint CD85j/LILRB1 on Malignant Plasma Cells Contributes to Immune Escape in Multiple Myeloma. Journal of Immunology, 200(8), pp. 2581 - 2591 . https://doi.org/10.4049/jimmunol.1701622 . ISSN: 0022-1767

Espigol-Frigolé, G.; Planas, E.; Lozano, E.; Corbera, M.; Terrades, N.; Prieto, S.; Garcia, A.; Hernández, J.; Grau Josep, M.; Cid, M.C. (2018). Expression and function of IL12/23 related cytokine subunits (p35, p40, and p19) in giant-cell arteritis lesions: contribution of p40 to Th1- and Th17-mediated inflammatory pathways. Frontiers in Immunology, 9, p. 809 . Institutional Repository . ISSN: 1664-3224

Fernandez de Larrea, Carlos; Isola, Ignacio; Pereira, Arturo; Teresa Cibeira, Ma; Magnano, Laura; Tovar, Natalia; Rodriguez-Lobato, Luis-Gerardo; Calvo, Xavier; Arostegui, Juan I.; Diaz, Tania; Lozano, Ester; Rozman, Maria; Yague, Jordi; Blade, Joan; Rosinol, Laura (2018). Evolving M-protein pattern in patients with smoldering multiple myeloma: impact on early progression. Leukemia, 32(6), pp. 1427 - 1434 . https://doi.org/10.1038/s41375-018-0013-4 . ISSN: 0887-6924

Diaz, T.; Rodriguez, V.; Lozano, E.; Mena, MP.; Calderon, M.; Rosinol, L.; Martinez, A.; Tovar, N.; Perez-Galan, P.; Blade, J.; Roue, G.; Fernandez de Larrea, C. (2017). The BET bromodomain inhibitor CPI203 improves lenalidomide activity in in vitro and in vivo models of multiple myeloma by synergistic blockade of Ikaros and Myc signaling. Haematologica, 102(10), pp. 1776 - 1784 . Institutional Repository . ISSN: 0390-6078

Lozano E.; Joller N.; Cao Y.; Kuchroo V.K,; Hafler D.A. (2013). The CD226/CD155 interaction regulates the proinflammatory (Th1/Th17)/anti-inflammatory (Th2) balance in humans. Journal of Immunology, 191(7), pp. 3673 - 3680 . ISSN: 0022-1767

Joller N.; Lozano E.; Burkett P.R.; Patel B.; Xiao S.; Zhu C.; Xia J.; Tan T.G.; Sefik E.; Yajnik V.; Sharpe A.H.; Quintana F.J.; Mathis D.; Benoist C.; Hafler D.A.; Kuchroo V.K. (2014). Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses. Immunity, 40(4), pp. 569 - 581 . ISSN: 1074-7613

Lozano E.; Dominguez-Villar M.; Kuchroo V.K,; Hafler D.A. (2012). The TIGIT/CD226 axis regulates human T cell function. Journal of Immunology, 188(8), pp. 3869 - 3975 . ISSN: 0022-1767

Beriou G.; Bradshaw E.M.; Lozano E.; Costantino C.M.; Hastings W.D.; Orban T.; Elyaman W.; Khoury S.J.; Kuchroo V.K,; Baecher-Allan C.; Hafler D.A. (2010). TGF-beta induces IL-9 production from human Th17 cells. Journal of Immunology, 185(1), pp. 46 - 54 . ISSN: 0022-1767

Isola, I.; Brasó-Maristany, F.; Moreno, D.F.; Mena, M.P.; Oliver-Calders, A.; Paré, L.; Rodríguez-Lobato, L.G.; Martin-Antonio, B.; Cibeira, M.T.; Bladé, J.; Rosiñol, L.; Prat, A.; Lozano, E.; Fernández de Larrea, C. (2021). Gene Expression Analysis of the Bone Marrow Microenvironment Reveals Distinct Immunotypes in Smoldering Multiple Myeloma Associated to Progression to Symptomatic Disease. Frontiers in Immunology, 12(792609), pp. 1 - 11 . Institutional Repository . ISSN: 1664-3224