Ester Lozano Garcia

Senior lecturer

Researcher ID: H-2215-2014

Knowledge area: Immunologia

Contact Information
Department of Cell Biology, Physiology and Immunology
Avinguda Diagonal, 643

elozano(a)ub.edu

Stays abroad in Research Centers

New Haven. UNITED STATES. 2010 (3 Years 5 Months) . Dept. Neurology and Immunobiology (Yale School of Medicine) . Postdoctoral

Academic training

Biologia . Universitat de Barcelona . 1994 . (Diploma / Degree / Activities)

Doctor de la Universitat de Barcelona . Universitat de Barcelona . 26/05/2008 . (Ph.D.)

Biotecnologia . Universitat de Barcelona . 1997 . (Official Master)

Activity interests

Mechanisms of immune regulation in humans . (01/03/2009)

immunotherapy
Immune Checkpoint

Projects

Identificación de los mecanismos inmunológicos que controlan la progresión a mieloma en los pacientes con mieloma quiescente 'non-evolving' y 'evolving' para el diseño de nuevas estrategias terapéuticas (Programa Nacional de Salud) . 2021 - 2023 . Ref.PI20/00436 . Instituto de Salud Carlos III . PI: Laura Rosiñol Dachs; Ester Lozano Garcia . (5 Researchers)

Mecanismos de control inmunológico involucrados en la progresión tras tratamiento en el mieloma múltiple () . 2017 - 2019 . Ref.PI16/00423 (PI044505) . Instituto de Salud Carlos III . PI: Carlos Fernández de Larrea

Journal Publications

Lozano, E.; Mena, M.P.; Garrabou, G.; Cardús, O.; Díaz, T.; Moreno, D.F.; Mañé-Pujol, J.; Oliver-Caldés, A.; Battram, A.; Tovar, N.; Cibeira, M.T.; Rodríguez-Lobato, L.G.; Bladé, J.; Fernández de Larrea, C.; Rosiñol L. (2024). Increased PVR Expression on Bone Marrow Macrophages May Promote Resistance to TIGIT Blockade in Multiple Myeloma. Clinical Cancer Research, 30(17), pp. 3944 - 3955 . Institutional Repository . ISSN: 1078-0432

Barroso, S.; Guitart-Mampel, M.; Garcia Garcia, F.J.; Cantó-Santos, J.; Valls-Roca, L.; Andújar-Sánchez, F.; Vilaseca-Capel, A.; Tobías, E.; Arias-Dimas, A.; Quesada-López, T.; Artuch, R.; Villaroya, F.; Giralt, M.; Martinez, E.; Lozano, E.; Garrabou, G. (2024). Metabolic, mitochondrial and inflammatory effects of efavirenz, emtricitabine and tenofovir disoproxil fumarate in asymptomatic antiretroviral-naïve people with HIV. International Journal of Molecular Sciences, 25(15) . https://doi.org/10.3390/ijms25158418 . ISSN: 1661-6596

Isola, I.; Brasó-Maristany, F.; Moreno, D.F.; Mena, M.P.; Oliver-Calders, A.; Paré, L.; Rodríguez-Lobato, L.G.; Martin-Antonio, B.; Cibeira, M.T.; Bladé, J.; Rosiñol, L.; Prat, A.; Lozano, E.; Fernández de Larrea, C. (2021). Gene Expression Analysis of the Bone Marrow Microenvironment Reveals Distinct Immunotypes in Smoldering Multiple Myeloma Associated to Progression to Symptomatic Disease. Frontiers in Immunology, 12(792609), pp. 1 - 11 . Institutional Repository . ISSN: 1664-3224

Lozano E.; Dominguez-Villar M.; Kuchroo V.K,; Hafler D.A. (2012). The TIGIT/CD226 axis regulates human T cell function. Journal of Immunology, 188(8), pp. 3869 - 3975 . ISSN: 0022-1767

Joller N.; Lozano E.; Burkett P.R.; Patel B.; Xiao S.; Zhu C.; Xia J.; Tan T.G.; Sefik E.; Yajnik V.; Sharpe A.H.; Quintana F.J.; Mathis D.; Benoist C.; Hafler D.A.; Kuchroo V.K. (2014). Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses. Immunity, 40(4), pp. 569 - 581 . ISSN: 1074-7613

Lozano, Ester; Mena, Mari-Pau; Díaz, Tania; Martin-Antonio, Beatriz; Leon, Sheila; Rodríguez-Lobato, Luis Gerardo; Oliver-Caldés, Aina; Cibeira, Maria Teresa; Bladé, Joan; Prat, Aleix; Rosinol, Laura; Fernández de Larrea, Carlos (2020). Nectin-2 Expression on Malignant Plasma Cells Is Associated With Better Response to TIGIT Blockade in Multiple Myeloma. Clinical Cancer Research, 26(17), pp. 4688 - 4698 . Institutional Repository . ISSN: 1078-0432

Lozano E.; Joller N.; Cao Y.; Kuchroo V.K,; Hafler D.A. (2013). The CD226/CD155 interaction regulates the proinflammatory (Th1/Th17)/anti-inflammatory (Th2) balance in humans. Journal of Immunology, 191(7), pp. 3673 - 3680 . ISSN: 0022-1767

Lozano, Ester; Diaz, Tania; Mena, Mari-Pau; Sune, Guillermo; Calvo, Xavier; Calderon, Marcos; Perez-Amill, Lorena; Rodriguez, Vanina; Perez-Galan, Patricia; Roue, Gael; Teresa Cibeira, M.; Rosinol, Laura; Isola, Ignacio; Rodriguez-Lobato, Luis-Gerardo; Martin-Antonio, Beatriz; Blade, Joan; Fernandez De larrea, Carlos (2018). Loss of the Immune Checkpoint CD85j/LILRB1 on Malignant Plasma Cells Contributes to Immune Escape in Multiple Myeloma. Journal of Immunology, 200(8), pp. 2581 - 2591 . https://doi.org/10.4049/jimmunol.1701622 . ISSN: 0022-1767

Lozano, E.; Segarra, M.; Corbera-Bellalta, M.; García-martínez, A.; Espigol-Frigolé, G.; Plà-Campo, A.; Hernández-Rodríguez, J.; Cid, M.C. (2010). Increased expression of the endothelin system in arterial lesions from patients with Giant-cell arteritis. Association between elevated endothelin plasma levels and the development of ischaemic events. Annals of the Rheumatic Diseases, 69, pp. 434 - 442 . ISSN: 0003-4967

Diaz, T.; Rodriguez, V.; Lozano, E.; Mena, MP.; Calderon, M.; Rosinol, L.; Martinez, A.; Tovar, N.; Perez-Galan, P.; Blade, J.; Roue, G.; Fernandez de Larrea, C. (2017). The BET bromodomain inhibitor CPI203 improves lenalidomide activity in in vitro and in vivo models of multiple myeloma by synergistic blockade of Ikaros and Myc signaling. Haematologica, 102(10), pp. 1776 - 1784 . Institutional Repository . ISSN: 0390-6078