Talia Velasco Hernandez

Talia Velasco Hernandez

Lecturer Professor

Knowledge area: Immunologia

Contact Information
Department of Biomedical Sciences


tvelasco(a)ub.edu

More Information: https://scholar.google.com/citations?user=RX2FIyIAAAAJ&hl=es

Academic training

p53 restoration delays the development of CML caused by p210BCR-ABL in a mouse model . Universidad de Salamanca . 10/06/2011 . (Ph.D.)

Research Projects

Evaluando LIMS1 como nueva diana terapéutica contra las células iniciadoras de la Leucemia Mieloide Aguda . 2024 - 2027 . Ref.PID2023-149758OB-I00 . Ministerio de Ciencia e Innovación . PI: Talia Velasco Hernandez
Aplicabilidad de las células CAR-T anti-CD4 (antiCD4-CAR) para la eliminación del reservorio latente del VIH-1 en personas que viven con VIH . 2023 - 2026 . Ref.PID2023-147320OB-I00 . Ministerio de Ciencia, Innovación y Universidades . PI: María Salgado
Acute Myeloid Leukemia initiating cells: Contribution of hypoxia/HIFpathway to chemoresistance and relapse . 2022 - 2025 . Ref.DJCLS 15R/2021 . Deutsche José Carreras Leukämie-Stiftung e.V. . PI: Pablo Menendez Bujan; Talia Velasco Hernandez
Identificación de nuevas dianas terapéuticas para evitar la recaída y quimioresistencia en Leucemia Mieloide Aguda . 2022 - 2023 . Ref.INVES223069VELA . Asociación Española Contra el Cáncer-Catalunya (AECC) . PI: Talia Velasco Hernandez

Journal Publications

Molina O; Ortega-Sabater C; Thampi N; Fernández-Fuentes N; Guerrero-Murillo M; Martínez-Moreno A; Vinyoles M; Velasco-Hernández T; Bueno C; Trincado JL; Granada I; Campos D; Giménez C; Boer JM; den Boer ML; Calvo GF; Camós M; Fuster JL; Velasco P; Ballerini P; Locatelli F; Mullighan CG; Spierings DCJ; Foijer F; Pérez-García VM; Menéndez P. (2024). Ongoing chromosomal instability across aneuploid subtypes of childhood B-cell Acute Lymphoblastic Leukemia associates with disease progression. EMBO Molecular Medicine . https://doi.org/10.1038/s44321-023-00006-w . ISSN: 1757-4676
Velasco-Hernandez, Talia; Trincado, Juan L.; Vinyoles, Meritxell; Closa, Adria; Martínez-Moreno, Alba; Gutiérrez-Agüera, Francisco; Molina, Oscar; Rodríguez-Cortez, Virginia C.; Ximeno-Parpal, Pau; Fernández-Fuentes, Narcís; Petazzi, Paolo; Beneyto-Calabuig, Sergi; Velten, Lars; Romecin, Paola; Casquero, Raquel; Abollo-Jiménez, Fernando; de la Guardia, Rafael D.; Lorden, Patricia; Bataller, Alex; Lapillonne, Hélène; Stam, Ronald W.; Vives, Susana; Torrebadell, Montserrat; Fuster, Jose L.; Bueno, Clara; Sarry, Jean-Emmanuel; Eyras, Eduardo; Heyn, Holger; Menéndez, Pablo (2024). Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells. Hemasphere, 8(2) . Institutional Repository . ISSN: 2572-9241
Bousquets-Muñoz, P.; Molina, O.; Varela, I.; Álvarez-Eguiluz, A.; Fernández-Mateos, J.; Gómez, A.; Sánchez, E.G.; Balbín, M.; Ruano, D.; Ramírez-Orellana, M.; Puente, X.S.; Menéndez, P.; Velasco-Hernández, T. (2024). Backtracking NOM1::ETV6 fusion to neonatal pathogenesis of t(7;12) (q36;p13) infant AML. Leukemia, 38, pp. 1808 - 1812 . Institutional Repository . ISSN: 0887-6924
Kodali S; Proietti L; Valcarcel G; López-Rubio AV; Pessina P; Eder T; Shi J; Jen A; Lupión-Garcia N; Starner AC; Bartels MD; Cui Y; Sands CM; Planas-Riverola A; Martínez A; Velasco-Hernandez T; Tomás-Daza L; Alber B; Manhart G; Mayer IM; Kollmann K; Fatica A; Menendez P; Shishkova E; Rau RE; Javierre BM; Coon J; Chen Q; Van Nostrand EL; Sardina JL; Grebien F; Di Stefano B. (2024). RNA sequestration in P-bodies sustains myeloid leukaemia. Nature Cell Biology . ISSN: 1465-7392
Lopez-Millan B; Rubio-Gayarre A; Vinyoles M; Trincado JL; Fraga MF; Fernandez-Fuentes N; Guerrero-Murillo M; Martinez A; Velasco-Hernandez T; Falgàs A; Panisello C; Valcarcel G; Sardina JL; López-Martí P; Javierre BM; Del Valle-Pérez B; García de Herreros A; Locatelli F; Pieters R; Bardini M; Cazzaniga G; Rodríguez-Manzaneque JC; Hanewald T; Marschalek R; Milne TA; Stam RW; Tejedor JR; Menendez P; Bueno C. (2024). NG2 is a target gene of MLL-AF4 that underlies glucocorticoid resistance in infant MLL-rearranged B-ALL by regulating NR3C1 expression. Blood . ISSN: 0006-4971
Sjövall D; Ghosh S; Fernandez-Fuentes N; Velasco-Hernandez T; Hogmalm A; Menendez P; Hansson J; Guibentif C; Jaako P. (2024). Defective ribosome assembly impairs leukemia stem cell function in a murine model of acute myeloid leukemia. Cell Reports . ISSN: 2211-1247
Aïda Falgàs; Rodrigo Lázaro Gorines; Samanta Romina Zanetti; Laura Rubio Pérez; Alba Martínez; Meritxell Vinyoles; Mercedes Guerrero Murillo; Narcís Fernández Fuentes; Heleia Roca; Néstor Tirado; Carla Panisello; Talia Velasco Hernández; Andrea Mayado; Alba Pérez Pons; Eulalia Genescà; Josep Maria Ribera; Jordi Ribera; Mireia Camos; Manuel Ramírez Orellan; Eduardo Anguita; Paola Ballerini; José Luis Fuster; Manel Juan; Europa Azucena González Navarro; Franco Locatelli; Ronald W Stam Sergi Querol; Pablo Velasco; Valentín Ortiz Maldonado; Nuria Martínez Cibrián; Julio Delgado; Alberto Orfao; Luis Álvarez Vallina; Clara Bueno; Pablo Menéndez (2025). A TIM-3-Fc decoy secreted by engineered T cells improves CD19 CAR-T cell therapy in B cell acute lymphoblastic leukemia. Blood . ISSN: 0006-4971