Thomas Stratmann

Senior lecturer

Knowledge area: Immunologia

Coordinador Local UB del Master Erasmus+ Leading International Vaccinology Education

Research group: Inflamació: Recerca bàsica i translacional

Contact Information
Department of Cell Biology, Physiology and Immunology
Diagonal 645, 3a planta
934021533
thomas.stratmann(a)ub.edu

Teaching

Immunologia

Màster d'Immunologia Avançada

Academic Training

Eine Vergleichende Untersuchung von Allergen Chargen . Phillips Universität Marburg . 01/05/1994 . (Diploma / Degree / Activities)

Functional Characterization of recombinant I-Ag7 . Phillips Universität Marburg . 04/11/2005 . (Ph.D.)

Research interests

Diabetes del tipo I, analisis de células T autoreactivas, vacunas de DNA para la prevencion del diabetes tipo I

Projects

INSULIN OCTAMERS FOR THE DETECTION OF LOW AFFINITY AUTOREACTIVE B CELLS . 2014 - 2015 . Ref.1-PNF-2014-174-A-V . Juvenile Diabetes Research Foundation . PI: Thomas Stratmann

Linfocitos B y T autoreactivos en la diabetes del tipo 1: Análisis funcional y desarrollo de estrategias de tratamiento . 2014 - 2016 . Ref.SAF2013-45140-R . Ministerio de Economia y Competitividad . PI: Joan Verdaguer (T. Stratmann I.P. local UB)

Biomarkers of Progression in the At-Risk Setting for Type 1 Diabetes . 2016 - 2017 . Ref.1-PNF-2016-336-S-B . Juvenile Diabetes Research Foundation . PI: Thomas stratmann

LINFOCITOS T Y B ANTI-PERIFERINA Y ANTI-CROMOGRANINA T AND B LYMPHOCYTE DURANTE EL DESARROLLO DE LA DIABETES MELLITUS TIPO 1 . 2017 - 2019 . Ref.SAF2016-77227-R . Ministerio de Economia y Competitividad . PI: Joan Verdaguer Autonell (Thomas Stratmann PI local UB)

Leading International Vaccinology Education Master Erasmus+ - Numero Proyecto oficial: 599318-EPP-1-2018-1-FR-EPPKA1-JMD-MOB . 2018 - 2025 . Ref.599318-EPP-1-2018-1-FR-EP . Unió Europea . PI: Christine Delprat (UCBL), Thomas Stratmann coordinador local UB

Journal Publications

Presa, M.; Ortizm AZ.; Garabatos, N.; Izquierdo, C.; Rivas, EI.; Teyton, L.; Mora, C.; Serreze, D.; Stratmann, T. (2013). Cholera toxin subunit B peptide fusion proteins reveal impaired oral tolerance induction in diabetes-prone but not in diabetes-resistant mice. European Journal of Immunology, 43(11), pp. 2969 - 2979 . ISSN: 0014-2980

Garabatos, N.; Alvarez, R.; Carrillo, J.; Carrascal, J.; Izquierdo, C.; Chapman¿, H.D.; Presa, M.; Mora, C.; Serreze, D.V.; Verdaguer, J.; Stratmann, T. (2014). In vivo detection of peripherin-specific autoreactive B cells during type 1 diabetes pathogenesis. Journal of Immunology, 192(7), pp. 3080 - 3090 . ISSN: 0022-1767

Saavedra-Ávila, N.A.; Segupta, U.; Sánchez, B.; Sala, E.; Haba, L.; Stratmann, T.; Verdaguer, J.; Mauricio, D.; Mezquita, B.; Ropero, A.B.; Nadal, A.; Mora, C. (2014). Cyclin D3 promotes pancreatic b-cell fitness and viability in a cell cycle-independent manner and is targeted in autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 111(33), pp. E3405 - E3414 . ISSN: 0027-8424

Stratmann, T. (2015). Cholera Toxin Subunit B as Adjuvant--An Accelerator in Protective Immunity and a Break in Autoimmunity. Vaccines, 3(3), p. 579-596 . Institutional Repository . ISSN: 2076-393X

Leeth, C.M.; Racine, J.; Chapman, H.D.; Arpa, B.; Carrillo, J.; Carrascal, J.; Wang, Q.; Ratiu, J.; Egia-Mendikute, L.; Rosell-Mases, E.; Stratmann, T.; Verdaguer, J.; Serreze, D.V. (2016). B-lymphocytes expressing an immunoglobulin specificity recognizing the pancreatic ß-cell autoantigen peripherin are potent contributors to type 1 diabetes development in NOD mice. Diabetes . ISSN: 0012-1797

Clemente-Casares, Xavier; Blanco, Jesus; Ambalavanan, Poornima; Yamanouchi, Jun; Singha, Santiswarup; Fandos, Cesar; Tsai, Sue; Wang, Jinguo; Garabatos, Nahir; Izquierdo, Cristina; Agrawal, Smriti; Keough, Michael B.; Yong, V. Wee; James, Eddie; Moore, Anna; Yang, Yang; Stratmann, Thomas; Serra, Pau; Santamaria, Pere (2016). Expanding antigen-specific regulatory networks to treat autoimmunity. Nature, 530(7591), pp. 434 - + . https://doi.org/10.1038/nature16962 . ISSN: 0028-0836

Espinosa-Carrasco, G.; Le Saout, C.; Fontanaud, P.; Stratmann, T.; Mollard, P.; Schaeffer, M.; Hernandez, J. (2018). CD4+ T Helper Cells Play a Key Role in Maintaining Diabetogenic CD8+ T Cell Function in the Pancreas. Frontiers in Immunology, 8, p. 2001 . Institutional Repository . ISSN: 1664-3224

Izquierdo C; Ortiz AZ; Presa M; Malo S; Montoya A; Garabatos N; Mora C; Verdaguer J; Stratmann T. (2018). Treatment of T1D via optimized expansion of antigen-specific Tregs induced by IL-2/anti-IL-2 monoclonal antibody complexes and peptide/MHC tetramers. Scientific Reports, 8(8106) . Institutional Repository . ISSN: 2045-2322

Marta Sisteré-Oró; Júlia Vergara-Alert; Thomas Stratmann; Sergi López-Serrano; Sonia Pina-Pedrero; Lorena Córdoba; Mónica Pérez-Maillo; Patrícia Pleguezuelos; Enric Vidal; Veljko Veljkovic; Joaquim Segalés; Jens Nielsen; Anders Fomsgaard; Ayub Darji (2019). Conserved HA-peptide NG34 formulated in pCMV-CTLA4-Ig reduces viral shedding in pigs after a heterosubtypic influenza virus SwH3N2 challenge. PLoS One, 14(3), p. e0212431 . Institutional Repository . ISSN: 1932-6203

Stratmann, T.; Corper, A. L.; Apostolopoulos, V.; Scott, C. A.; Garcia, K. C.; Kang, A. S.; Wilson, I. A.; Teyton, L. (2000). A structural framework for deciphering the link between I-Ag7 and murine autoimmune diabetes. Science, 288, pp. 505 - 511 . ISSN: 0036-8075