Marta Pascual Sanchez

Associate professor

Researcher ID: Q-8103-2018

Knowledge area: Biologia Cel.lular

Research group: IP Mecanismes de Neurodegeneració i Neuroprotecció

Contact Information
Department of Cell Biology, Physiology and Immunology
Av. Diagonal 645, Ed Annex 1a planta
934037115
marpascual(a)ub.edu

Academic Training

Ciències Biologiques . Universitat de BArcelona . 01/06/1993 . (Diploma / Degree / Activities)

Ciències Biologiques . Universitat de Barcelona . 09/03/2001 . (Ph.D.)

Projects

Alteraciones en la conexión gabaérgica septohipocámpica en la enfermedad de alzheimer. Implicaciones terapéuticas . 2012 - 2014 . Ref.PI11/00704 . Fondo de Investigación Sanitaria. Instituto de Salud Carlos III . PI: Marta Pascual Sánchez

Mecanismes de Neurodegeneració i Neuroprotecció . 2022 - 2025 . Ref.SGR2021-00885 . Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR) . PI: Marta Pascual Sánchez

Mención de Excelencia Maria de Maetzu al Institut de Neurociències de la Universitat de Barcelona (UBNEURO) . 2018 - 2022 . Ref.MDM-2017-0729 . Ministerio de Economia, Industria y Competitividad . PI: Jordi Alberch Vie

Nuevas funciones de la reelina en el desarrollo neuronal y en la patogénesis de la enfermedad de Alzheimer . 2023 - 2026 . Ref.PID2022-138105OB-C21 . Ministerio de Ciencia e Innovación (MICINN) . PI: Eduardo Soriano Garcia; Yasmina Manso Sanz

Enfermedades neurodegenerativas . 2012 - 2024 . Ref.CB06/05/0098 . Ministerio de Sanidad y Consumo . PI: Eduardo Soriano Garcia

Journal Publications

Rubio, Sara E.; Vega-Flores, German; Martinez, Albert; Bosch, Carles; Perez-Mediavilla, Alberto; del Rio, Joaquin; Gruart, Agnes; Maria Delgado-Garcia, Jose; Soriano, Eduardo; Pascual, Marta (2012). Accelerated aging of the GABAergic septohippocampal pathway and decreased hippocampal rhythms in a mouse model of Alzheimer's disease. The FASEB Journal , 26(11), pp. 4458 - 4467 . https://doi.org/10.1096/fj.12-208413 . ISSN: 0892-6638

Vega-Flores, G.; Rubio, S.E.; Jurado-Parras, M.T.; Gómez-Climent, M.A.; Hampe, C.S.; Manto, M.; Soriano, E.; Pascual, M.; Gruart, A.; Delgado-García, J.M. (2014). The GABAergic Septohippocampal Pathway Is Directly Involved in Internal Processes Related to Operant Reward Learning. Cerebral Cortex, 24(8), pp. 2093 - 2107 . https://doi.org/10.1093/cercor/bht060 . ISSN: 1047-3211

Soler, H; Dorca-Arévalo, J; González, M; Rubio, SE; Ávila, J; Soriano, E; Pascual, M. (2017). The GABAergic septohippocampal connection is impaired in a mouse model of tauopathy. Neurobiology of Aging, 49, pp. 40 - 51 . https://doi.org/10.1016/j.neurobiolaging.2016.09.006 . ISSN: 0197-4580

Davila-Bouziguet, Eva; Targa-Fabra, Georgina; Avila, Jesus; Soriano, Eduardo; Pascual, Marta (2019). Differential accumulation of Tau phosphorylated at residues Thr231, Ser262 and Thr205 in hippocampal interneurons and its modulation by Tau mutations (VLW) and amyloid-beta peptide. Neurobiology of Disease, 125, pp. 232 - 244 . https://doi.org/10.1016/j.nbd.2018.12.006 . ISSN: 0969-9961

Giralt, A.; Brito, V.; Pardo, M.; Rubio, S.E.; Marion-Poll, L.; Martín-Ibáñez, R.; Zamora-Moratalla, A.; Bosch, C.; Ballesteros, J.J.; Blasco, E.; García-Torralba, A.; Pascual, M.; Pumarola, M.; Alberch, J.; Ginés, S.; Martín, E.D.; Segovia, J.; Soriano, E.; Canals, J.M. (2020). Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation. Experimental Neurology, 323, p. 113095 . Institutional Repository . ISSN: 0014-4886

Coccia, E.; Planells-Ferrer, L.; Badillos-Rodríguez, R.; Pascual, M.; Segura, M.; Fernández-Hernández, R.; López-Soriano, J.; Garí, E.; Soriano, E.; Barneda-Zahonero, B.; Moubarak, R.S.; Pérez-García, M.J.; Comella, J.X. (2020). SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L. Cell Death and Disease, 11(2), p. 82 . Institutional Repository . ISSN: 2041-4889

Arnau Sans-Dublanc1; Adrià Razzauti; Srinidhi Desikan; Marta Pascual; Hannah Monyer; Carlos Sindreu (2020). Septal gabaergic inputs to CA1 govern contextual memory retrieval. Science Advances, 6(44) . Institutional Repository . ISSN: 2375-2548

Dávila-Bouziguet, Eva; Casòliba-Melich, Arnau; Targa-Fabra, Georgina; Galera-López, Lorena; Ozaita, Andrés; Maldonado, Rafael; Ávila, Jesús; Delgado-García. José M.; Gruart, Agnès; Soriano, Eduardo; Pascual, Marta (2022). Functional protection in J20/VLW mice: a model of non-demented with Alzheimer's disease neuropathology. Brain, 145(2), pp. 729 - 743 . ISSN: 0006-8950

Vílchez-Acosta A, Manso Y, Cárdenas A, Elias-Tersa A, Martínez-Losa M, Pascual M, Álvarez-Dolado M, Nairn AC, Borrell V, Soriano E. (2022). Specific contribution of Reelin expressed by Cajal-Retzius cells or GABAergic interneurons to cortical lamination. Proceedings of the National Academy of Sciences of the United States of America - PNAS, Vol. 119 (No. 37) . https://doi.org/10.1073/pnas.2120079119 . ISSN: 0027-8424

Martínez-Mármol R; Muhaisen A; Cotrufo T; Roselló-Busquets C; Ros O; Hernaiz-Llorens M; Pérez-Branguli F; Andrés RM; Parcerisas A; Pascual M; Ulloa F; Soriano E. (2023). Syntaxin-1 is necessary for UNC5A-C/Netrin-1-dependent macropinocytosis and chemorepulsion. Frontiers In Molecular Neuroscience, 16(1253954), pp. 1 - 19 . https://doi.org/10.3389/fnmol.2023.1253954 . ISSN: 1662-5099