Tamara Cruz Santa Cruz

Lecturer Professor

ORCID: 0000-0002-6362-6348

Scopus Author ID: 56178204100

Researcher ID: AAH-8835-2019

Knowledge area: Immunologia

Research group: Immunopathology and translational research in respiratory diseases

Contact Information
Department of Cell Biology, Physiology and Immunology

cruz(a)ub.edu

Academic Training

Inmunologia Avanzada . Universidad de Barcelona - Universidad Autonoma de Barcelona . 01/09/2012 . (Official Master)

Biotecnologia . Universitat de Lleida . 30/06/2011 . (Diploma / Degree / Activities)

Characterization of the pulmonary and systemic immune response in relation with lung stem cells in patients with COPD . Fundació Clinic per la Recerca Biomedica - IDIBAPS . 21/07/2017 . (Ph.D.)

Research interests

Early Identification and Personalized Treatment of Pulmonary Fibrosis in Interstitial Lung Diseases

Ex vivo lung fibrosis model as a platform to investigate immune-fibrosis interactions

Characterization of the aging and immunological effect on the stage pulmonary fibrosis patients

Projects

Doctorat industrial en col.laboració amb empresa: Loop Diagnostics,S.L . 2025 - 2028 . Ref.2025DI00060 . Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR) . PI: Tamara Cruz Santa Cruz

Desentrañando las alteraciones en la respuesta a la terapia antifibrótica . 2025 - 2027 . Separ . PI: Tamara Cruz Santa Cruz

Identifying new biomarkers for progressive pulmonary fibrosis and response to therapy, moving towards precision medicine: the FIBROPROG study. . 2024 - 2026 . Ref.PI23/00924 . Instituto de Salud Carlos III . PI: Tamara Cruz Santa Cruz y Jacobo Sellares

From COPD Heterogeneity to Personalized Medicine (COPD HOPE) . 2022 - 2025 . Ref.ID 100010434, LCF/BQ/PI22/11910042 . La Caixa . PI: Tamara Cruz Santa Cruz

Reveling the molecular mechanisms of progressive pulmonary fibrosis.
. 2024 - 2026 . Separ . PI: Tamara Cruz Santa Cruz y Fernanda Hernandez

Journal Publications

Hernandez-Gonzalez, F.; Pietrocola, F.; Cameli, P.; Bargagli, E.; Prieto-González, S.; Cruz, T.; Mendoza, N.; Rojas, M.; Serrano, M.; Agustí, A.; Faner, R.; Gómez-Puerta, J.A.; Sellares, J. (2024). Exploring the Interplay between Cellular Senescence, Immunity, and Fibrosing Interstitial Lung Diseases: Challenges and Opportunities. International Journal of Molecular Sciences, 25(14) . https://doi.org/10.3390/ijms25147554 . ISSN: 1661-6596

Tamara Cruz, Paula A Agudelo Garcia, Julián A Chamucero-Millares, Anna Bondonese, Nilay Mitash, John Sembrat, Tracy Tabib, Wenping Zhang, Nouraie Seyed, Victor Peters, Sean Stacey, Dario Vignali, Ana L Mora, Robert Lafyatis, Mauricio Rojas (2023). End-Stage Idiopathic Pulmonary Fibrosis Lung Microenvironment Promotes Impaired NK Activity. The Journal of Immunology . https://doi.org/10.4049/jimmunol.2300182 . ISSN: 0022-1767

Cruz, T.; Mendoza, N.; Casas-Recasens, S.; Noell, G.; Hernandez-Gonzalez, F.; Frino-Garcia, A.; Alsina-Restoy, X.; Molina, M.; Rojas, M.; Agustí, A.; Sellares, J.; Faner, R. (2023). Lung immune signatures define two groups of end-stage IPF patients. Respiratory Research, 24(1), p. 236 . https://doi.org/10.1186/s12931-023-02546-8 . ISSN: 1465-993X

Early events marking lung fibroblast transition to profibrotic state in idiopathic pulmonary fibrosis (2023). Minxue Jia, Lorena Rosas, Maria G. Kapetanaki, Tracy Tabib, John Sebrat, Tamara Cruz, Anna Bondonese, Ana L. Mora, Robert Lafyatis, Mauricio Rojas and Panayiotis V. Benos. Respiratory Research . https://doi.org/10.1186/s12931-023-02419-0 . ISSN: 1465-9921

Tamara Cruz, Minxue Jia, John Sembrat, Tracy Tabib, Naomi Agostino, Tullia C. Bruno, Dario Vignali, Pablo Sanchez, Robert Lafyatis, Ana L. Mora, Panayiotis Benos and Mauricio RojasMauricio Rojas (2021). Reduced Proportion and Activity of Natural Killer Cells in the Lung of Patients with Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine . https://doi.org/10.1164/rccm.202012-4418LE . ISSN: 1073-449X