Raul Lopez Arnau

Professor agregat

Researcher ID: Q-5896-2018

Àrea de coneixement : Farmacologia

Grup de Recerca: Neuropsicofarmacologia dels derivats amfetamínics i altres noves substàncies psicoactives

Informació de contacte
Departament de Farmacologia, Toxicologia i Química Terapèutica
Avinguda Joan XXIII 27-31
934021314
raullopezarnau(a)ub.edu

Formació acadèmica

Química

Doctor en Farmacologia

Màster en Recerca, Desenvolupament i Control de Medicaments

Projectes

New generation of drugs protecting against neurotoxic industrial chemicals (NeuroTICs) . 2021 - 2024 . Ref.SPS.MYP G5852 . Organización del Tratado del Atlántico Norte (OTAN) . IP: Raul Lopez Arnau

Detección precoz del potencial adictivo de nuevas drogas psicoestimulantes. Una nueva estrategia para la prevención de un posterior abuso (PREVENPS) . 2020 - 2023 . Ref.PID2019-109390RB-I00 . Ministerio de Ciencia, Innovación y Universidades . IP: Elena Escubedo Rafa; Raul Lopez Arnau

Early and effective detection of addictive and hallucinogen potential in the next generation of psychoactive drugs to speed up the implementation of control measures by the EU . 2022 - 2024 . Ref.101045825 . EU Research training Network . IP: J Camarasa/ J Kehr/ X Berzosa/ M Schmid/ M Solinas

Setting-up scientific-based evidences of the harmful potential of new psychostimulants and psychedelics, as a tool for preventing health risks in the frame of the Drug Early Warning Systems . 2023 - 2026 . Ref.PID2022-137541OB-I00 . Ministerio de Ciencia e Innovación . IP: Raul Lopez Arnau

Publicacions rellevants

López-Arnau, R.; Martínez-Clemente, J.; Pubill, D.; Escubedo, E.; Camarasa, J. Comparative neuropharmacology of three psychostimulant cathinone derivatives: butylone, mephedrone and methylone. En British Journal of Pharmacology. Volum 167. 2012 . https://doi.org/10.1111/j.1476-5381.2012.01998.x

López-Arnau,R; Luján,M.A.; Duart-Castells,L:; Pubill, D.; Camarasa, J.; Valverde, O.; Escubedo, E. Exposure of adolescent mice to 3,4-methylenedioxypyrovalerone increases the psychostimulant, rewarding and reinforcing effects of cocaine in adulthood. En British Journal of Pharmacology. Volum 174. Número 10. 2017 . Repositori Institucional

Nadal-Gratacós, N.; Alberto-Silva, A.S.; Rodríguez-Soler, M.; Urquizu, E.; Espinosa-Velasco, M.; Jäntsch, K.; Holy, M.; Batllori, X.; Berzosa, X.; Pubill, D.; Camarasa, J.; Sitte, H.H.; Escubedo, E.(corresponding); López-Arnau, R. Structure-Activity relationship of novel second-generation synthetic cathinones: Mechanism of action, locomotion, reward, and immediate-early genes. En Frontiers in Pharmacology. Volum 12. 2021 . Repositori Institucional

Duart-Castells, L.; Nadal-Gratacós, N.; Muralter, M.; Puster, B.; Berzosa, X.; Estrada-Tejedor, R.; Niello, M.; Bhat, S.; Pubill, D.; Camarasa, J.; Sitte H.H.; Escubedo, E.; López-Arnau, R. Role of amino terminal substitutions in the pharmacological, rewarding and psychostimulant profiles of novel synthetic cathinones. En Neuropharmacology. Volum 186. Número 108475 (Online). 2021 . Repositori Institucional

Riley, A.L.; Nelson, K.H.; To, P.; López-Arnau, R.; Xu, P.; Wang, D.; Wang, Y.; Shen, H.W.; Kuhn, D.M.; Angoa-Perez, M.; Anneken, J.H.; Muskiewicz, D.; Hall, F.S. Abuse potential and toxicity of the synthetic cathinones (i.e., 'Bath salts'). En Neuroscience and Biobehavioral Reviews. Volum 110. 2020 . https://doi.org/10.1016/j.neubiorev.2018.07.015

Núria Nadal-Gratacós, Edwin Ríos-Rodríguez, David Pubill, Xavier Batllori, Jorge Camarasa, Elena Escubedo, Xavier Berzosa, Raúl López-Arnau. Structure-Activity Relationship of N-Ethyl-Hexedrone Analogues: Role of the α-Carbon Side-Chain Length in the Mechanism of Action, Cytotoxicity, and Behavioral Effects in Mice. En ACS Chemical Neuroscience. 2023 . https://doi.org/10.1021/acschemneuro.2c00772

Puigseslloses, P.; Nadal-Gratacós, N.; Ketsela, G.; Weiss, N.; Berzosa, X.; Estrada-Tejedor, R.; Islam, M.N.; Holy, M.; Niello, M.; Pubill, D.; Camarasa, J.; Escubedo, E.; Sitte, H.H.; López-Arnau, R. Structure-activity relationships of serotonergic 5-MeO-DMT derivatives: insights into psychoactive and thermoregulatory properties. En Molecular Psychiatry. 2024

Espinosa-Velasco, E.; Castro-Zavala, A.; Reguilón, M.; Gallego-Landín, I.; Bellot, M.; Rublinetska, O.; Valverde, O.; Rodríguez-Arias, M.; Nadal-Gratacós, N.; Berzosa, X.; Gómez-Canela, C.; Carbó, M.; Camarasa, J.; Escubedo, E.; López-Arnau, R.; Pubill, D. Sex differences in the effects of N-ethylpentylone in youngCD1 mice: insights on behaviour, thermoregulation andearly gene expression. En British Journal of Pharmacology. 2024 . https://doi.org/10.1111/bph.16506