Teaching Innovation Groups:
ORFILA: Grup d'Innovació Docent de Toxicologia
Contact Information
Department of Pharmacology, Toxicology and Medicinal Chemistry
Facultat Farmàcia. Diagonal 643 934024531 roglans(a)ub.edu
Academic training
Llicenciada en Farmàcia
Doctora en Farmàcia
Relevant publications
Baena, Miguel; Sanguesa, Gemma; Hutter, Natalia; Maria Beltran, Jose; Maria Sanchez, Rosa; Roglans, Nuria; Alegret, Marta; Carlos Laguna, Juan. Liquid fructose in Western-diet-fed mice impairs liver insulin signaling and causes cholesterol and triglyceride loading without changing calorie intake and body weight.
In
Journal of Nutritional Biochemistry.
Volume 40.
2017
. Institutional RepositoryBentanachs, R.; Velázquez, A.M.; Sánchez, R.M.; Alegret, M.; Laguna, J.C.; Roglans, N. El ácido bempedoico como activador PPARalpha: nuevas perspectivas para el tratamiento de la esteatosis hepática en un modelo experimental de rata hembra.
In
Clínica e Investigación en Arteriosclerosis.
2021
. Institutional RepositoryJC Laguna; N Roglans, R Bentanachs. Pemafibrato: ¿un fracaso PROMINENTe o una necesidad urgente de reposicionamiento terapéutico?.
In
Clínica e Investigación en Arteriosclerosis.
Volume 35.
2023Di Veroli B; Bentanachs R; Roglans N; Alegret M; Giona L; Profumo E; Berry A; Saso L; Laguna JC; Buttari B. Sex Differences Affect the NRF2 Signaling Pathway in the Early Phase of Liver Steatosis: A High-Fat-Diet-Fed Rat Model Supplemented with Liquid Fructose.
In
Cells.
Volume 13.
Number 15.
2024
. https://doi.org/10.3390/cells13151247Bentanachs Roger; Miro Lluisa; Sanchez Rosa M.; Ramirez-Carrasco Patricia; Amat Concepcio; Alegret Marta; Perez Anna; Roglans Nuria; Laguna Juan C. Pemafibrate abrogates SLD in a rat experimental dietary model inducing a shift in fecal bile acids and microbiota composition.
In
Biomedicine & Pharmacotherapy.
Volume 177.
2024
. Institutional RepositoryBentanachs, R.; Velazquez, A.; Roglans, N.; Alegret, M.; Laguna, JC. Increased DNL and PNPLA3 expression by liquid fructose are essential in the production of fatty liver and hypertriglyceridemia in non-obese HFD-fed rat model.
In
Atherosclerosis.
Volume 355.
2022Bentanachs, R.; Velázquez, A.; Roglans, N.; Laguna, JC.; Alegret, M. Ketohexokinase inhibition by bempedoic acid reduces fructose consumption in female rats fed a high-fat diet.
In
Atherosclerosis.
Volume 355.
2022Bentanachs Raset R.; Velazquez A. M.; Sala-Vila A.; Lazaro I.; Rodriguez-Morato J.; Sanchez R. M.; Alegret M.; Roglans N.; Laguna J. C. en Increased DNL and PNPLA3 expression by liquid fructose are essential in the production of fatty liver and hypertriglyceridemia in non-obese HFD-fed rat model.
In
Atherosclerosis.
Volume 355.
2022Puertas-Umbert, L.; Alonso, J.; Blanco-Casoliva, L.; Almendra-Pegueros, R.; Camacho, M.; Rodríguez-Sinovas, A.; Galán, M.; Roglans, N.; Laguna, JC.; Martínez-Gonzalez, J.; Rodríguez, C. Inhibition of ATP-citrate lyase by bempedoic acid protects against abdominal aortic aneurysm formation in mice.
In
Biomedicine & Pharmacotherapy.
Volume 184.
Number 117876.
2025
. https://doi.org/10.1016/j.biopha.2025.117876