JORDI BORRELL HERNANDEZ

Full professor

Researcher ID: M-1390-2014

Knowledge area: Química Física

Research group: Nanobioengineering and Bioelectrònics (SIC-BIO)

Contact Information
Department of Pharmacy and Pharmaceutical Technology and Physical Chemistry
Av. Diagonal, 643
934035986
jordiborrell(a)ub.edu

Research interests

Nanostructure of biomembranes

Liposomes, Monolayers and Supported Lipid Bilayers

Chemistry and physics of lipids of membranes

Membrane structure protein

Projects

Microscopio de barrido de fuerzas elèctricas para medidas electrofisiológicas a la nanoescala . 2016 - 2019 . Ref.TEC2016-79156-P . Ministerio de Economia y Competitividad . PI: Gabriel Gomila LLuch

Microscopic origin of electrostatic surfaces potential of phospholipid Langmuir-Blodgett monolayers . 2017 - 2018 . Ref.ATR17/18 . Institut de Nanociència i Nanotecnologia de la UB. IN2UB. . PI: Carles Calero

Breaking the borders of antimicrobial resistance: Searching new antimicrobial compounds against multi-drug resistant bacteria: A study of policationic AMPs and lipid nanoparticles . 2018 - 2021 . Fundació La Marató de TV3 . PI: Miguel Viñas Ciordia

Nanobienginyeria i Bioelectrònica SCI-BIO . 2018 - 2021 . Ref.2017SGR1079 . Generalitat de Catalunya . PI: Josep Samitier Martí

Relevant publications

Picas, L.; Milhiet, P.E.; Hernández-Borrell, J. Atomic force microscopy: a versatile tool to probe the physical and chemical properties of supported membranes at the nanoscale. In Chemistry and Physics of Lipids. Number 165. 2012 . https://doi.org/10.1016/j.chemphyslip.2012.10.005

Suárez-Germà, C.; Domènech, O.; Montero, M.T.; Hernández-Borrell,J. Effect of lactose permesase presence on the strucure and nanomechanics of two-component supported lipid bilayers. In Biochimica et Biophysica Acta-Biomembranes. Volume 1382. Number 3. 2014 . https://doi.org/10.1016/j.bbamem.2013.11.015

Vázquez-González, M.L.; Calpena, M.C.; Domènech, Ò.; Montero,M.T.; Borrell, J. Enhanced topical delivery of hyaluronic acid encapsulated in liposomes: A surface-dependent phenomenon. In Colloids and Surfaces B-Biointerfaces. Volume 134. 2015 . https://doi.org/10.1016/j.colsurfb.2015.06.029

Borrell, J.H.; Montero, M.T.; Morros, A.; Domènech, Ò. Unspecific membrane protein-lpid recognition: combination of AFM imaging, force spectroscopy, DSC and FRET measurements. In Journal of Molecular Recognition. Volume 28. Number 11. 2015 . https://doi.org/10.1002/jmr.2483

Borrell, Jordi H.; Teresa Montero, M.; Domenech, Oscar. Mapping Phase Diagrams of Supported Lipid Bilayers by Atomic Force Microscopy. In Microscopy Research and Technique. Volume 80. Number 1. 2017 . https://doi.org/10.1002/jemt.22655

Borrell, J.H.; Domènech, Ò. Critical Temperature of 1-Palmitoyl-2-oleoyl-Sn-glycero-3-phosphoethanolamine Monolayers and Its Possible Biological Relevance. In Journal of Physical Chemistry B. Volume 121. 2017 . https://doi.org/10.1021/acs.jpcb.7b04021

Botet-Carreras, Adria; Montero, M. Teresa; Domenech, Oscar; Borrell, Jordi H. Effect of cholesterol on monolayer structure of different acyl chained phospholipids. In Colloids and Surfaces B-Biointerfaces. Volume 174. 2019 . https://doi.org/10.1016/j.colsurfb.2018.11.040

Vázquez-González, M.L.; Botet-Carreras, A.; Domènech, Ò.; Montero, M.T.; Borrell, J.H. Planar lipid bilayers formed from thermodynamically-optimized liposomes as new featured carriers for drug delivery systems through human skin. In International Journal of Pharmaceutics. Volume 563. 2019 . https://doi.org/10.1016/j.ijpharm.2019.03.052

Borrell, J.H.; Domènech, O.;Keough, K.M.W. Membrane protein-lipid interactions: physics and chemistry in the bilayer. In Membrane protein-lipid interactions: physics and chemistry in the bilayer. Springer International Publishing AG. 2016 . doi:10.1007/978-3-319-30277-5

Borrell, J.H.; Montero, M.T.; Vázquez, M.L.; Domènech, Ò. The lipid-protein interplay in efflux pumps. In Recent Advances in Pharmaceutical Sciences VI. Volume. VI . Research Signpost. 2016