Ouldouz Ghashghaei

Ouldouz Ghashghaei

Adjunct part-time

ORCID: 0000-0002-5524-3697
Scopus Author ID: 55994907700
Researcher ID: B-9362-2018
Knowledge area: Química Orgànica

Research group:

Contact Information
Department of Pharmacology, Toxicology and Medicinal Chemistry
Faculty of Pharmacy, Av. Joan XXIII, 27-31

ghashghaei(a)ub.edu

Academic training

Chemistry
Experimental and Industrial Organic Chemistry
Organic Chemistry

Projects

TREX2 targeting psoriasis and atopic dermatitis. F2I-FVal_2020-013 . 2021 - 2021 . Fundació Bosch i Gimpera de la Universitat de Barcelona . PI: Concepcio Soler Prat
CHEMBIO NANOMED . 2017 - 2021 . Ref.2017SGR1439 . Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR) . PI: Fernando Albericio Palomera
Identificación, síntesis y evaluación toxicológica de molécula propia antidetonante . 2018 - 2019 . Ref.309799 . Repsol YPF, S.A. . PI: Francisco Javier Luque Garriga
TET2 modulation for myelodysplastic syndrome (MDS) and other diseases Acronim TET2_plus F21-FVal_2018_007 . 2018 - 2019 . Fundació Bosch i Gimpera de la Universitat de Barcelona . PI: Xavier Barril Alonso
Development of TET2 modulators for cancer treatment . 2019 - 2020 . Ref.310258 . Fundació Privada Institut d'Investigació Oncològica de Vall d'Hebron (VHIO) . PI: Xavier Barril Alonso
Reacciones Multicomponente: descubrimiento, desarrollo y aplicaciones en Biomedicina . 2020 - 2023 . Ref.PID2019-107991RB-I00 . Ministerio de Ciencia, Innovación y Universidades . PI: Rodolfo Lavilla Grifols; Maria Carmen Escolano Miron
Targeting TREX2 as innovative keratinocyte-based therapy for psoriasis.CI20-00169 (CAIXAIMPULSE VALIDATE) . 2020 - 2022 . Ref.CI20-00169 . Fundació Caixa de Pensions 'La Caixa' . PI: Concepcio Soler Prat

Relevant publications

Ouldouz Ghashghaei; Marina Pedrola; Francesca Seghetti; Victor V. Martin; Ricardo Zavarce; Michal Babiak; Jiri Novacek; Frederick Hartung; Katharina M. Rolfes; Thomas Haarmann-Stemmann[c]; and Rodolfo Lavilla*. 'Extended Multicomponent Reactions with Indole Aldehydes: Access to Unprecedented Polyheterocyclic Scaffolds, Ligands of the Aryl Hydrocarbon Receptor. In Angewandte Chemie-International Edition. Volume 60. Number 5. 2021 . https://doi.org/10.1002/anie.202011253
Ouldouz Ghashghaei, Pau Nadal-Rodríguez Rodolfo Lavilla. Development of Heterocyclic Multicomponent Reactions through Guided Exploration: Direct, Reasonable and Unpredictable Processes. In Synlett. Volume 33. Number 9. 2022 . https://doi.org/10.1055/a-1750-3185;ArtID:st-2021-a0473-a
Nicole D. Barth, Lorena Mendive-Tapia, Ramon Subiros-Funosas, Ouldouz Ghashghaei, Rodolfo Lavilla, Laura Maiorino, Xue-Yan He, Ian Dransfield, Mikala Egeblad, Marc Vendrell. A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy-induced Cancer Cell Death. In Angewandte Chemie-International Edition. Volume 61. Number 5. 2021 . https://doi.org/10.1002/anie.202113020

Patents, Software and Database

TREX2 inhibitors (European Patent Convention Countries, 26/04/2023)