Elena Sánchez López

Elena Sánchez López

Investigadora Requalificació (Lector)

ORCID: 0000-0003-2571-108X

Research group: SISTEMES NANOSTRUCTURATS D'ALLIBERAMENT CONTROLAT DE FÀRMACS

Grup d'Innovació Docent en Anàlisi Instrumental Farmacèutic

Contact Information
Rector's Office
Av. Joan XXIII, 27-31
696793679
esanchezlopez(a)ub.edu

Academic training

Pharmacy
Master in Research, Development and Drug Control
Animal experimentation course
Experimental Master in Pharmaceutical Sciences

Research interests

Development of Polymeric nanoparticles for Alzheimer's disease
Development,characteritzation and in vivo efficacy assesment of polymeric nanoparticles for glaucoma
Development of protein liposomes for ocular drug delivery
Development of polymeric nanoparticles encapsulating nonsteroidal anti-inflammatory drugs for ocular drug delivery
Evaluation of cytotoxicity and cellular uptake of nanostrutured systems for controlled drug delivery
Freeze dry of pharmaceutical formulations

Projects

Sistemes nanoestructurats d'alliberament controlat de fàrmacs . 2014 - 2017 . Ref.2014SGR1023 . Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR) . PI: Maria Luisa Garcia Lopez
Analysis of the stress mechnisms during sterilization and stabilization by lyophilisation of nanostructured biomaterials and the effects on their biopharmaceutical profiles . 2012 - 2014 . Ref.MAT2011-26994 . Ministerio de Ciencia e Innovación (MICINN) . PI: Maria Luisa Garcia López
SIIN2Brain: safe implementation of innovative nanomedicines for Alzheimer's disease . 2015 - 2015 . Ref.Ayudas UB Horitzon 2020 . Vicerectorat de Recerca, Innovació i Transferència . PI: Maria Luisa Garcia López
Aplicación de criterios de calidad basada en el diseño al proceso de liofilización de sistemas nanoestructurados para el tratamiento de enfermedades neurodegenerativas . 2015 - 2017 . Ref.MAT2014-59134-R . Ministerio de Ciencia e Innovación (MICINN) . PI: Maria Luisa Garcia Lopez
Colloidal systems for ocular drug delivery . 2017 - 2017 . Ref.309246 . Terra di Cuma . PI: Maria Luisa Garcia Lopez
Colloidal system for ocular drug delivery . 2017 - 2017 . Ref.309246 . Terra di Cuma . PI: Maria Luisa Garcia Lopez
Design of an age-dependent corneal membrane model for in vitro interaction studies of biodegradable polymeric nanoparticles. In vitro/ex vivo/in vivo correlation . 2018 - 2019 . Ref.24345 . Institut de Nanociència i Nanotecnologia de la UB. IN2UB. . PI: Elena Sanchez Lopez
Tiquets d'innovació UB. Viabilitat i caracterització fisicoquímica de sistemes nanoestructurats per administració oral i tòpica . 2020 - 2021 . Technology dedicated to care España, S.L. . PI: Maria Luisa García i Elena Sánchez López

Relevant publications

Sánchez-López, E.; Ettcheto, M.; Egea, M.A.; Espina, M.; Calpena, A.C.; Folch, J.; Camins, A.; García, M.L. New Potential Strategies for Alzheimer's Disease Prevention: Pegylated biodegradable Dexibuprofen nanospheres administration to APPswe/PS1dE9. In Nanomedicine: Nanotechnology, Biology and Medicine. Volume 2017. Number 13. 2017 . https://doi.org/10.1016/j.nano.2016.12.003
Ettcheto M.; Sánchez-López E.; Pons L.; Busquets O.; Olloquequi J.; Beas-Zarate C.; Pallas M.; García M.L.; Auladell C.; Folch J.; Camins A. Dexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways. In Redox Biology. Volume 13. 2017 . Institutional Repository
Sánchez-López, E.; Cano, A.; Ettcheto, M.; Egea, M.A.; Espina, M.; Calpena, A.C.; Folch, J.; Camins,A.; García, M.L. Dexibuprofen loaded PEGylated nanospheres for Alzheimer's disease treatment. In Journal of Controlled Release. Number 259. 2017 . https://doi.org/10.1016/j.jconrel.2017.03.086
Sánchez-López, E.; Egea, M.A; Davis, B.M.; Guo, L.; Espina, M.; Silva,A.M.; Calpena,A.C.; Souto,E.B.; Ravindran, N.; Ettcheto, M.; Camins, A.; García, M.L.; Cordeiro, M.F. Memantine loaded PEGylated biodegradable nanoparticles for the treatment of glaucoma. In Small. 2018 . https://doi.org/10.1002/smll.201701808
Sánchez-López, E.: Espina, M.; Doktorovova, S.; Souto, E.B.; García, M.L. Lipid nanoparticles (SLN, NLC): Overcoming the anatomical and physiological barriers of the eye - Part II Ocular drug loaded lípid nanoparticles. In European Journal of Pharmaceutics and Biopharmaceutics. Volume 110. 2017 . https://doi.org/10.1016/j.ejpb.2016.10.013
Sánchez-López, E.; Espina, M.; Doktorovova, S.; Souto, E.B.; García, M.L. Lipid nanoparticles (SLN, NLC): Overcoming the anatomical and physiological barriers of the eye - Part I - Barriers and determining factors in ocular delivery. In European Journal of Pharmaceutics and Biopharmaceutics. Volume 100. 2017 . https://doi.org/10.1016/j.ejpb.2016.10.009
Cano, A.; Sánchez-López, E.; Espina, M.; Egea, M.A.; García, M.L. Polymeric nanoparticles of (-)-epigallocatechin gallate: A new formulation for the treatment of ocular diseases. In Journal of Controlled Release. Volume 259. 2017 . https://doi.org/10.1016/j.jconrel.2017.03.046
Sánchez-López,E.; Egea, M.A.; Cano, A.; Espina, M.; Calpena, A.C.; Ettcheto, M.; Camins, A.; Souto, E.B.; Silva, A.M.; García, M.L. PEGylated PLGA naospheres optimized by design of experiments for ocular administration of dexibuprofen-in vitro, ex vivo and in vivo characterization. In Colloids and Surfaces B-Biointerfaces. Volume 145. 2016 . Institutional Repository
Sánchez-López, E.; Ettcheto, M.; Egea, M.A; Espina, M.; Cano, A; Calpena,A.C.; Camins, A.; Carmona, N.; Silva,A.M.; Souto,E.B.; García, M.L. Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterization. In Journal of Nanobiotechnology. Volume 16. Number 32. 2018 . Institutional Repository
Elena Sánchez-López; Anna Paús; Ignacio Pérez-Pomeda; Ana Calpena;Isabel Haro and María José Gómara. Lipid Vesicles Loaded with an HIV-1 Fusion Inhibitor Peptide as a Potential Microbicide. In Pharmaceutics. Volume 12. Number 6. 2020 . Institutional Repository

Patents, Software and Database

Liposomes for the treatment of ocular pathologies (EP 3603621 A1 i US 10,835,494 B2) (ITALY, 31/07/2018)
Composition comprising nanoparticles, method for the preparation of a composition comprising nanoparticles and uses of the composition for dental treatment (---, 12/06/2020)