ELENA ESCUBEDO RAFA

ELENA ESCUBEDO RAFA

Full professor

ORCID: 0000-0002-5078-366X
Scopus Author ID: 7003451798
Researcher ID: K-5295-2014
Knowledge area: Farmacologia

Research group: Neuropsicofarmacologia dels derivats amfetamínics i altres noves substàncies psicoactives

Teaching Innovation Groups: ORFILA: Grup d'Innovació Docent de Toxicologia

Contact Information
Department of Pharmacology, Toxicology and Medicinal Chemistry
Avda. Diagonal, s/n
934024531
eescubedo(a)ub.edu

Academic profile

Farmacologia i terapèutica
Neurofarmacologia
Recerca i Desenvolupament de Fàrmacs
Drogodependència

Academic training

Licenciatura en Farmacia
Doctor en Farmacia
Master in Bioinformatics for Health Sciences

Research interests

Neuropsicofarmacologia dels derivats amfetamínics
Addicció, cognició i plasticitat

Projects

Estudio, en modelos murinos, de la interacción farmacocinética y farmacodinámica entre el alcohol y la metilendioxipirovalerona . 2016 - 2019 . Ref.2016I004 . Ministerio de Sanidad, Servicios Sociales e Igualdad . PI: Elena Escubedo Rafa
Detección precoz del potencial adictivo de nuevas drogas psicoestimulantes. Una nueva estrategia para la prevención de un posterior abuso (PREVENPS) . 2020 - 2023 . Ref.PID2019-109390RB-I00 . Ministerio de Ciencia, Innovación y Universidades . PI: Elena Escubedo Rafa; Raul Lopez Arnau
Early and effective detection of addictive and hallucinogen potential in the next generation of psychoactive drugs to speed up the implementation of control measures by the European Union . 2022 - 2024 . Ref.101045825 . EU Research training Network . PI: J Camarasa/J Kehr/X Berzosa/M Schmid/M Solinas
New generation of drugs protecting against neurotoxic industrial chemicals (NeuroTICs) . 2021 - 2024 . Ref.SPS.MYP G5852 . Organización del Tratado del Atlántico Norte (OTAN) . PI: Raul Lopez Arnau
Setting-up scientific-based evidence of the harmful potential of new psychostimulants and psychedelics as a tool for preventing health risks in the frame of drug early warning systems. (NPSrisks) . 2023 - 2026 . Ref.PID2022-137541OB-I00 . Ministeri de Ciència, Innovació i Universitats - MCIU . PI: Elena Escubedo Rafa

Relevant publications

Ciudad-Roberts, A.; Camarasa, J.; Ciudad, C.; Pubill, D.; Escubedo, E. Alcohol enhances the psychostimulant and conditioning effects of mephedrone in adolescent mice. Postulation of unique roles of D3 receptors and BDNF in place preference acquisition. In British Journal of Pharmacology. Number 172. 2015 . https://doi.org/10.1111/bph.13266
Abad, Sonia; Ramon, Carla; Pubill, David; Camarasa, Jorge; Camins, Antonio; Escubedo, Elena. Adolescent exposure to MDMA induces dopaminergic toxicity in substantia nigra and potentiates the amyloid plaque deposition in the striatum of APPswe/PS1dE9 mice. In Biochimica et Biophysica Acta-Molecular Basis of Disease. Volume 1862. Number 9. 2016 . https://doi.org/10.1016/j.bbadis.2016.06.016
López-Arnau,R; Luján,M.A.; Duart-Castells,L:; Pubill, D.; Camarasa, J.; Valverde, O.; Escubedo, E. Exposure of adolescent mice to 3,4-methylenedioxypyrovalerone increases the psychostimulant, rewarding and reinforcing effects of cocaine in adulthood. In British Journal of Pharmacology. Volume 174. Number 10. 2017 . Institutional Repository
Duart-Castells, L.; López-Arnau, R.; Vizcaíno, S.; Camarasa, J.; Pubill, D.; Escubedo, E.(*) * Corresponding author. 7,8-Dihydroxyflavone blocks the development of behavioral sensitization to
MDPV, but not to cocaine: Differential role of the BDNF-TrkB pathway. In Biochemical Pharmacology. Volume 163. 2019 . Institutional Repository
Duart-Castell, L.; Blanco-Gandía, M.C.; Ferrer-Pérez, C.; Puster, B.; Pubil, D.; Miñarro, J.; Escubedo, E.; Rodríguez-Arias, M. Cross-reinstatement between 3,4-methylenedioxypyrovalerone (MDPV) and cocaine using conditioned place preference. In Progress in Neuro-Psychopharmacology & Biological Psychiatry. Volume 100. Number 109876. 2020 . https://doi.org/10.1016/j.pnpbp.2020.109876
Abad, Sonia; Ramon-Duaso, Carla; Lopez-Arnau, Raul; Folch, Jaume; Pubill, David; Camarasa, Jordi; Camins, Antoni; Escubedo, Elena. Effects of MDMA on neuroplasticity, amyloid burden and phospho-tau expression in APPswe/PS1dE9 mice. In Journal of Psychopharmacology. Volume 33. Number 9. 2019 . https://doi.org/10.1177/0269881119855987
Bedrossiantz, J.; Bellot, M.; Dominguez-García, P.; Faria, M.; Prats, E.; Gómez-Canela, C.; López-Arnau, R.; Escubedo, E.; Raldúa, D. A Zebrafish Model of Neurotoxicity by Binge-Like Methamphetamine Exposure. In Frontiers in Pharmacology. Volume 12. 2021 . Institutional Repository
Espinosa-Velasco, M.; Reguilón, MD.; Bellot, M.; Nadal-Gratacós, N.; Berzosa, X.; Puigseslloses, P.; Gómez-Canela, C.; Rodríguez-Arias, M.; Pubill, D.; Camarasa, J.; Escubedo, E.; López-Arnau, R. Behavioural and neurochemical effects after repeated administration of N-ethylpentylone (ephylone) in mice. In Journal of Neurochemistry. Volume 160. Number 2. 2022 . Institutional Repository
Nadal-Gratacós, N.; Alberto-Silva, A.S.; Rodríguez-Soler, M.; Urquizu, E.; Espinosa-Velasco, M.; Jäntsch, K.; Holy, M.; Batllori, X.; Berzosa, X.; Pubill, D.; Camarasa, J.; Sitte, H.H.; Escubedo, E.(corresponding); López-Arnau, R. Structure-Activity relationship of novel second-generation synthetic cathinones: Mechanism of action, locomotion, reward, and immediate-early genes. In Frontiers in Pharmacology. Volume 12. 2021 . Institutional Repository
Nadal-Gratacós, N.; Lleixà, E.; Gibert-Serramià, M.; Estrada-Tejedor, R.; Berzosa, X.; Batllori, X.; Pubill, D.; Camarasa, J.; Escubedo, E.; López-Arnau, R. Neuropsychopharmacology of Emerging Drugs of Abuse: meta- and para-Halogen-Ring-Substituted &-PVP ('flakka') Derivatives. In International Journal of Molecular Sciences. Volume 23. 2022 . Institutional Repository

Other activities

6 Trams de recerca/ 6 Sexenios de investigación 2018
7 Trams de docència / 7 Quinquenios de docencia 2017