AXEL BIDON-CHANAL BADIA

AXEL BIDON-CHANAL BADIA

Senior lecturer

ORCID: 0000-0002-1666-1490
Knowledge area: Química Física

Research group: Biologia Computacional i Disseny de Fàrmacs

Contact Information
Department of Food Science and Gastronomy
Campus de l'Alimentació de Torribera. Despatx 14, Edifici Verdaguer, Av. Prat de la Riba 171
934033788
abidonchanalb(a)ub.edu

Academic training

Llincenciat
Doctor

Projects

Unraveling the molecular mechanism of nitrosative stress resistance in tuberculosis (NOstress) . 2008 - 2012 . Ref.223335 . Unió Europea . PI: Francisco Javier Luque Garriga
Estrés nitrosativo y tuberculosis: Aproximación bioinformática hacia nuevas estrategias terapéuticas . 2010 - 2013 . Ref.PIB2010AR-00455 . Ministerio de Ciencia e Innovación (MICINN) . PI: Fco.Javier Luque Garriga
Mitochondrial transport mechanism at the molecular level . 2011 - 2013 . Agence Nationale de la Recherche (ANR) . PI: Eva Pebay-Peyroula
Desarrollo de nuevas metodologías y tecnologías emergentes de evidenciación de la eficacia de alimentos con propiedades de salud, para la reducción de riesgos de patologías crónicas en la edad media de vida (CENIT HENUFOOD) . 2011 - 2012 . Ref.CENIT HENUFOOD . Ministerio de Industria, Turismo y Comercio . PI: Fco.Javier Luque Garriga
Explorando nuevas estrategias terapéuticas para el tratamiento de enfermedades infecciosas y parasitarias . 2012 - 2014 . Ref.SAF2011-27642 . Ministerio de Ciencia e Innovación (MICINN) . PI: Fco.Javier Luque Garriga
Quimioinformàtica (Cenit HENUFOOD) . 2012 - 2013 . Ref.307219 . Universitat de Lleida (UdL) . PI: Axel Bidon-Chanal Badia; Fco.Javier Luque Garriga
Desenvolupament de llibreria virtual d'anàlegs de nucleòsids . 2013 - 2014 . Ref.307559 . Plasmia Biotech, S.L. . PI: Xavier Barril Alonso
Xarxa de Referència d'R+D+I en Química Teòrica i Computacional XRQTC 2014 . 2014 - 2014 . Ref.307645 . Departament d'Economia i Finances de la Generalitat de Catalunya . PI: Francesc Illas Riera
Biologia Computacional i Disseny de Fàrmacs . 2014 - 2017 . Ref.2014SGR1189 . Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR) . PI: Francisco Javier Luque Garriga
FRAGments training NETwork (FRAGNET) . 2016 - 2020 . Ref.675899 . Unió Europea . PI: Xavier Barril Alonso

Relevant publications

Stephanie Ravaud, Axel Bidon-Chanal, Iulia Blesneac, Paul Machillot, Céline Juillan-Binard, Francois Dehez, Chris Chipot, and Eva Pebay-Peyroula. Impaired transport of nucleotides in a mitochondrial carrier explains severe human genetic diseases. In ACS Chemical Biology. Volume 7. Number 7. 2012 . https://doi.org/10.1021/cb300012j
Bidon-Chanal, A.; Fuertes, A.; Alonso, D.; Pérez, D. I.; Martínez, A.; Luque, F. J.; Medina, M. Evidence for a new binding mode to GSK-3: Allosteric regulation by the marine compound palinurin. In European Journal of Medicinal Chemistry. Volume 60. 2013
Bidon-Chanal, A.; Krammer, E-M.; Blot,D.; Pebay-Peyroula, E.; Chipot, C.; Ravaud, S.; Dehez, F. How do Membrane Transporters Sense pH? The case of the Mitochondrial ADP–ATP Carrier. In Journal of Physical Chemistry Letters. Number 4. 2013 . https://doi.org/10.1021/jz401847d
Singh, S.; Thakur, N.; Oliveira, A.; Petruk, A.A.; Hade, M.D.; Sethi, D.; Bidon-Chanal, A.; Martí, M.A.; Datta, H.; Parkesh, R.; Estrin, D.A.; Luque, F.J.; Dikshit, K.L. Mechanistic Insight into the Enzymatic Reduction of Truncated Hemoglobin N of Mycobacterium tuberculosis: Role of the CD Loop and Pre-A motif in Electron Cycling. In Journal of Biological Chemistry. Number 289. 2014 . https://doi.org/10.1074/jbc.M114.578187
Knipp, M.; Ogata, H.; Soavi, G.; Cerullo, G.; Allegri, A.; Abbruzzetti, S.; Bruno, S.; Viappiani, C.; Bidon-Chanal, A.; Luque, F. J. Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7. In F1000Research. Volume 4. 2015 . Institutional Repository
Zamudio-Vázquez, R.; Ivanova, S.; Moreno, M.; Hernandez-Alvarez, M.I.; Giralt, E.; Bidon-Chanal, A.; Zorzano, A.; Albericio, F.; Tulla-Puche, J. A new quinoxaline-containing peptide induces apoptosis in cancer cells by autophagy modulation. In Chemical Science. Number 6. 2015 . Institutional Repository
Ruiz-Rodriguez, J.; Miguel, M.; Preciado, S.; Acosta, G. A.; Adan, J.; Bidon-Chanal, A.; Luque, F. J.; Mitjans, F.; Lavilla, R.; Albericio, F. Polythiazole linkers as functional rigid connectors: a new RGD cyclopeptide with enhanced integrin selectivity. In Chemical Science. Volume 5. Number 10. 2014 . https://doi.org/10.1039/c4sc00572d
Estarellas, C.; Seira, C.; Luque, F. J.; Bidon-Chanal, A. Understanding the kinetics of ligand binding to globins with molecular dynamics simulations: the necessity of multiple state models. In Drug Discovery Today: Technologies. Volume 17. 2015 . https://doi.org/10.1016/j.ddtec.2015.09.002
Pesce, A.; Bustamante, J. P.; Bidon-Chanal, A.; Boechi, L.; Estrin, D.; Luque, F. J.; Sebilo, A.; Guertin, M.; Bolognesi, M.; Ascenzi, P.; Nardini, M. The N-terminal pre-A region of Mycobacterium tuberculosis 2/2HbN promotes NO-dioxygenase activity. In The FEBS Journal. Volume 283. Number 2. 2016 . https://doi.org/10.1111/febs.13571
Valverde, E.; Seira, C.; McBride, A.; Binnie, M.; Luque, F. J.; Webster, S. P.; Bidon-Chanal, A.; Vazquez, S. Searching for novel applications of the benzohomoadamantane scaffold in medicinal chemistry: Synthesis of novel 11β-HSD1 inhibitors. In Bioorganic & Medicinal Chemistry. Volume 23. Number 24. 2015 . https://doi.org/10.1016/j.bmc.2015.11.004